Tobias Cantz

Medizinische Hochschule Hannover — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index4.5kcitations150works5.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Pluripotent Stem Cells Research(56), CRISPR and Genetic Engineering(46), Liver physiology and pathology(38), Pancreatic function and diabetes(18), Renal and related cancers(13)

Publications150 total

Nucleoside-Modified mRNA Encoding Alpha-Galactosidase A Reverses Fabry Disease Phenotypes in Human IPSC-Derived Cardiomyocytes
2025
A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis
Journal of Biological Chemistry·2025Open Access
iPSC-based hepatic organoids reveal a heterozygous MYO5B variant as driver of intrahepatic cholestasis
Hepatology Communications·2025· 1 citedOpen Access
Somatische genomische Therapien – Neue Chancen und Herausforderungen in der Biomedizin
Zeitschrift für medizinische Ethik·2025
Neue „somatische genomische Therapien“
Zeitschrift für medizinische Ethik·2025Open Access
“Snip, snip, cure”? Philosophical, legal and biomedical perspectives on novel somatic genomic therapies
Medicine Health Care and Philosophy·2025Open Access
PAM-interacting domain turn-helix 51 motifs can improve Cas9–SpRY activity
Nucleic Acids Research·2025Open Access
Identification and functional validation of miR-190b-5p and miR-296-3p as novel therapeutic attenuators of liver fibrosis
Journal of Hepatology·2024· 5 citedOpen Access
Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
Cell Reports Medicine·2024· 5 citedOpen Access
A spatiotemporal atlas of mouse liver homeostasis and regeneration
Nature Genetics·2024· 58 cited
Impaired transitioning of the FXR ligand binding domain to an active state underlies an FXR-associated PFIC phenotype
2024Open Access
Impaired transitioning from an inactive to an active state of FXR underlies a PFIC5 phenotype
Zeitschrift für Gastroenterologie·2024
Patient-specific hepatobiliary organoids elucidate functional alterations in intrahepatic cholestasis
Zeitschrift für Gastroenterologie·2024
Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells
International Journal of Molecular Sciences·2023· 3 citedOpen Access
Generation of Human 293-F Suspension NGFR Knockout Cells Using CRISPR/Cas9 Coupled to Fluorescent Protein Expression
Methods in molecular biology·2023· 2 cited
Issue Cover
Liver International·2022
Corrigendum to ‘Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model’ [J Hepatol (2021) 1420-1433]
Journal of Hepatology·2022· 3 cited
Extrahepatic manifestations of progressive familial intrahepatic cholestasis syndromes: Presentation of a case series and literature review
Liver International·2022· 29 citedOpen Access
Introduction to Genome Editing in Induced Pluripotent Stem Cells, Gametes, and Embryos
2022· 1 cited
KIF12 variants and disturbed hepatocyte polarity in children with a phenotypic spectrum of cholestatic liver disease
Zeitschrift für Gastroenterologie·2022· 3 cited
page 1 of 8Next →

Frequent Co-authors

Michael Ott(21), Axel Schambach(19), Amar Deep Sharma(17), Michael P. Manns(15), Hans R. Schöler(14), Malte Sgodda(9), Doris Steinemann(8), Qinggong Yuan(7), Asha Balakrishnan(6), Reto Eggenschwiler(6), Guangqi Song(5), Zhen Dai(5), Marcos J. Araúzo‐Bravo(5), Arndt Vogel(5), Nils Pfaff(5), Thomas Moritz(5), Eva Warlich(4), Dong‐Wook Han(4), Nico Lachmann(4), Boris Greber(4)