David J. Dowling

Boston Children's Hospital — United States

Immunology and Microbiology · Life Sciences

30h-index3.0kcitations88works9.22yr avg
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Research Topics

Immune Response and Inflammation(33), Immunotherapy and Immune Responses(26), SARS-CoV-2 and COVID-19 Research(17), Neonatal Respiratory Health Research(14), Influenza Virus Research Studies(11)

Publications86 total

Discovery of a small molecule TLR3 agonist adjuvant
Nature Communications·2025Open Access
Deep phenomics of PRR agonist activated human blood
The Journal of Immunology·2025
Incorporating meningeal immunity into vaccine development
Nature Communications·2025· 1 citedOpen Access
Nanomedicine and Spleen-Targeting Strategies for Precision Immunomodulation: Advances, Challenges, and Future Perspectives
ACS Nano·2025· 4 cited
Deep Phenomics of Pattern Recognition Receptor Agonist Specific Activation of Human Blood
2025Open Access
mRNA vaccines: miRNA-based controlled biodistribution and directed adjuvantation
Trends in Immunology·2025· 3 citedOpen Access
<scp>OMIP</scp> ‐ <scp>111</scp> : Immune‐Profiling of T Helper 1 (Th1), Th2, and Th17 Signatures in Murine Splenocytes by Targeting Intracellular Cytokines
Cytometry Part A·2025· 4 citedOpen Access
Product and trial design considerations on the path towards a vaccine to combat opioid overdose
npj Vaccines·2025· 4 citedOpen Access
BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice
Vaccine·2025· 2 citedOpen Access
Protocol for measuring anti-fentanyl antibodies in mouse serum by enzyme-linked immunosorbent assay
STAR Protocols·2024Open Access
An ionic liquid-based adjuvant for modulating cellular and humoral immune responses
Journal of Controlled Release·2024· 6 cited
The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo
iScience·2024· 4 citedOpen Access
Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70
Science Translational Medicine·2024· 30 cited
Need for strategic communications and stakeholder engagement to advance acceptability of an overdose preventing vaccine targeting fentanyl
Vaccine·2024· 4 citedOpen Access
From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation
Science Advances·2024· 13 citedOpen Access
BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice
2024Open Access
Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro
Communications Biology·2024· 11 citedOpen Access
Immune-profiling of T helper 1 (Th1), Th2 and Th17 signatures in murine splenocytes by targeting intracellular cytokines
2024Open Access
CHAPTER ONE Podcasting the Pandemic: Beyond the NPR Revolution
Columbia University Press eBooks·2024
Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen
npj Vaccines·2023· 19 citedOpen Access
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Frequent Co-authors

Ofer Levy(39), Simon D. van Haren(15), Etsuro Nanishi(14), Francesco Borriello(10), Soumik Barman(10), Byron Brook(9), Ilana Bergelson(8), Sandra M. O’Neill(8), Manisha Menon(8), Dheeraj Soni(8), Spencer E. Brightman(7), Marisa E. McGrath(6), Carly Dillen(6), Timothy R. O’Meara(6), Hyuk‐Soo Seo(6), Sirano Dhe‐Paganon(6), Matthew B. Frieman(6), Joann Diray‐Arce(6), Lindsey R. Baden(6), Al Ozonoff(6)