Sebastiano Rontauroli

University of Modena and Reggio Emilia — Italy

Medicine · Health Sciences

15h-index638citations42works1.72yr avg
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Research Topics

Myeloproliferative Neoplasms: Diagnosis and Treatment(34), Chronic Myeloid Leukemia Treatments(17), Kruppel-like factors research(15), Acute Myeloid Leukemia Research(12), Eosinophilic Disorders and Syndromes(10)

Publications42 total

Combined MEK and JAK inhibition reduces osteopontin plasma level and bone marrow fibrosis in a myelofibrosis mouse model
Blood Cancer Journal·2025Open Access
Unravelling molecular determinants of ruxolitinib treatment response in myelofibrosis using single cell multiomics
Blood·2025Open Access
CD44 Participates to Extramedullary Haematopoiesis Onset by Mediating the Interplay Between Monocytes and Haematopoietic Stem Cells in Myelofibrosis
Journal of Cellular and Molecular Medicine·2025Open Access
Supra-Physiological Levels of Magnesium Counteract the Inhibitory Effect of Zoledronate on RANKL-Dependent Osteoclastogenesis
Biology·2025Open Access
Chromosome 9p trisomy increases stem cells clonogenic potential and fosters T-cell exhaustion in JAK2-mutant myeloproliferative neoplasms
Leukemia·2024Open Access
Targeting exhausted cytotoxic T cells through <scp>CTLA</scp>‐4 inhibition promotes elimination of neoplastic cells in human myelofibrosis xenografts
American Journal of Hematology·2024· 10 citedOpen Access
Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms
Blood·2023Open Access
Clonal dynamics and copy number variants by single‐cell analysis in leukemic evolution of myeloproliferative neoplasms
American Journal of Hematology·2023· 15 citedOpen Access
Inhibition of ERK1/2 signaling prevents bone marrow fibrosis by reducing osteopontin plasma levels in a myelofibrosis mouse model
Leukemia·2023· 20 citedOpen Access
Novel Molecular Insights into Leukemic Evolution of Myeloproliferative Neoplasms: A Single Cell Perspective
International Journal of Molecular Sciences·2022· 9 citedOpen Access
Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition
Blood·2022
P999: ERK1/2 INHIBITION REDUCES OSTEOPONTIN PLASMA LEVELS AND BONE MARROW FIBROSIS IN A MYELOFIBROSIS MOUSE MODEL
HemaSphere·2022Open Access
P983: SINGLE CELL ANALYSIS ALLOWS THE EARLY DETECTION OF LEUKEMIC CLONES IN MPN PATIENTS
HemaSphere·2022Open Access
P987: A DIFFERENT BALANCE IN OXIDATIVE STRESS RESPONSE IN CALR AND JAK2 MUTATED MYELOFIBROSIS PATIENTS CORRELATES WITH CLINICAL OUTCOME
HemaSphere·2022Open Access
P1000: INCREASED PLASMA LEVELS OF LNCRNAS ARE POTENTIAL PROGNOSTIC BIOMARKERS IN MYELOFIBROSIS
HemaSphere·2022Open Access
The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis
Antioxidants·2022· 17 citedOpen Access
Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms
Blood·2021· 1 cited
Increased Plasma Levels of lncRNAs LINC01268, GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis
Cancers·2021· 19 citedOpen Access
Gene expression profile correlates with molecular and clinical features in patients with myelofibrosis
Blood Advances·2021· 11 citedOpen Access
Mutated clones driving leukemic transformation are already detectable at the single-cell level in CD34-positive cells in the chronic phase of primary myelofibrosis
npj Precision Oncology·2021· 15 citedOpen Access
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Frequent Co-authors

Rossella Manfredini(41), Elisa Bianchi(35), Enrico Tagliafico(33), Paola Guglielmelli(30), Chiara Carretta(26), Alessandro M. Vannucchi(25), Sandra Parenti(23), Elena Genovese(21), Roberta Zini(20), Lara Tavernari(20), Simona Salati(18), Ruggiero Norfo(17), Samantha Ruberti(17), Margherita Mirabile(15), Zelia Prudente(14), Valentina Pennucci(13), Niccolò Bartalucci(13), Chiara Rossi(13), Selene Mallia(13), Vittorio Rosti(12)