Ruggiero Norfo

University of Modena and Reggio Emilia — Italy

Medicine · Health Sciences

17h-index1.7kcitations59works7.62yr avg
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Research Topics

Myeloproliferative Neoplasms: Diagnosis and Treatment(31), Acute Myeloid Leukemia Research(18), Chronic Myeloid Leukemia Treatments(16), Kruppel-like factors research(14), Hematopoietic Stem Cell Transplantation(13)

Publications59 total

Combined MEK and JAK inhibition reduces osteopontin plasma level and bone marrow fibrosis in a myelofibrosis mouse model
Blood Cancer Journal·2025Open Access
Unravelling molecular determinants of ruxolitinib treatment response in myelofibrosis using single cell multiomics
Blood·2025Open Access
CD44 Participates to Extramedullary Haematopoiesis Onset by Mediating the Interplay Between Monocytes and Haematopoietic Stem Cells in Myelofibrosis
Journal of Cellular and Molecular Medicine·2025Open Access
Supra-Physiological Levels of Magnesium Counteract the Inhibitory Effect of Zoledronate on RANKL-Dependent Osteoclastogenesis
Biology·2025Open Access
Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis
Nature Communications·2025· 2 citedOpen Access
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis
Science Translational Medicine·2024· 20 citedOpen Access
Chromosome 9p trisomy increases stem cells clonogenic potential and fosters T-cell exhaustion in JAK2-mutant myeloproliferative neoplasms
Leukemia·2024Open Access
Targeting exhausted cytotoxic T cells through <scp>CTLA</scp>‐4 inhibition promotes elimination of neoplastic cells in human myelofibrosis xenografts
American Journal of Hematology·2024· 10 citedOpen Access
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
Nature Immunology·2024· 36 citedOpen Access
Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms
Blood·2023Open Access
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
Nature Communications·2023· 19 citedOpen Access
Ancient genomic linkage couples metabolism with erythroid development
2023· 3 citedOpen Access
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
Nature Genetics·2023· 130 citedOpen Access
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
Zenodo (CERN European Organization for Nuclear Research)·2023· 3 citedOpen Access
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells
Blood·2023· 6 citedOpen Access
A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis
2023· 5 citedOpen Access
Ancient Synteny Links Metabolism with Erythroid Development
SSRN Electronic Journal·2023Open Access
Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms
Blood·2022
An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis
Blood·2022
Deciphering <i>TP53</i> mutant Cancer Evolution with Single-Cell Multi-Omics
2022· 12 citedOpen Access
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Frequent Co-authors

Rossella Manfredini(23), Elisa Bianchi(19), Roberta Zini(17), Paola Guglielmelli(17), Adam J. Mead(16), Enrico Tagliafico(16), Valentina Pennucci(15), Simona Salati(14), Joana Carrelha(13), Sebastiano Rontauroli(13), Sten Eirik W. Jacobsen(12), Supat Thongjuea(11), Samantha Ruberti(11), Sérgio Ferrari(11), Alba Rodríguez-Meira(10), Alessandro M. Vannucchi(10), Claus Nerlov(9), Tiziana Fanelli(9), Zelia Prudente(9), Bethan Psaila(8)