Samantha Ruberti

Medicine · Health Sciences

13h-index608citations28works0.02yr avg
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Research Topics

Myeloproliferative Neoplasms: Diagnosis and Treatment(17), Kruppel-like factors research(12), Chronic Myeloid Leukemia Treatments(11), Acute Myeloid Leukemia Research(5), Chronic Lymphocytic Leukemia Research(5)

Publications28 total

Real-World Apremilast Use for Treatment of Plaque Psoriasis in Italy: Patient Perspective, Characteristics, and Clinical Outcomes from the DARWIN Study
Advances in Therapy·2023· 2 citedOpen Access
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment
Haematologica·2021· 10 citedOpen Access
The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs
Haematologica·2019· 16 citedOpen Access
Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma
Leukemia·2019· 109 cited
Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants
Scientific Reports·2019· 63 citedOpen Access
PB2097 METABOLIC STARVATION TRIGGERED BY L‐ASPARAGINASE SENSITIZES MULTIPLE MYELOMA CELLS TO PROTEASOME INHIBITORS BY INDUCING DNA DAMAGE ACCUMULATION
HemaSphere·2019Open Access
Erwinia Chrysantemi-Derived L-Asparaginase Strongly Enhances Proteasome Inhibitors Activity By Deregulating Cell Metabolic Programs
Blood·2018
Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells
Blood·2018· 1 cited
Role of <scp>TGF</scp>‐β1/miR‐382‐5p/<scp>SOD</scp>2 axis in the induction of oxidative stress in <scp>CD</scp>34+ cells from primary myelofibrosis
Molecular Oncology·2018· 26 citedOpen Access
Abstract 793: The novel Bruton's tyrosine kinase inhibitor ARQ531 disrupts survival signaling and triggers apoptosis in AML cells
Cancer Research·2018
Calreticulin Affects Hematopoietic Stem/Progenitor Cell Fate by Impacting Erythroid and Megakaryocytic Differentiation
Stem Cells and Development·2017· 24 citedOpen Access
The Role of the Axis TGF-β1/Mir-382-5p/SOD2 in the Induction of Oxidative Stress in CD34+ Hematopoietic Stem/Progenitor Cells from Primary Myelofibrosis
Blood·2017
Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients
Leukemia·2017· 36 citedOpen Access
Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells
Oncotarget·2017· 53 citedOpen Access
miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6
Oncotarget·2017· 18 citedOpen Access
Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis
International Journal of Molecular Sciences·2017· 13 citedOpen Access
MAF Induces Inflammatory Mediators Involved in the Pathogenesis of Primary Myelofibrosis
Blood·2016
MiR-494-3p Overexpression Leads to SOCS6 Downregulation and Supports Megakaryocytopoiesis in Primary Myelofibrosis CD34+ Hematopoietic Stem/Progenitor Cells
Blood·2016
miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of <i>MXD1</i>
Stem Cells and Development·2016· 26 citedOpen Access
Integrative Analysis of Copy Number and Gene Expression Data Suggests Novel Pathogenetic Mechanisms in Primary Myelofibrosis
Blood·2015
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Frequent Co-authors

Roberta Zini(21), Elisa Bianchi(21), Simona Salati(21), Rossella Manfredini(21), Enrico Tagliafico(18), Valentina Pennucci(17), Paola Guglielmelli(17), Sebastiano Rontauroli(17), Zelia Prudente(17), Alessandro M. Vannucchi(15), Ruggiero Norfo(14), Chiara Rossi(12), Carmela Mannarelli(10), Vittorio Rosti(10), Sérgio Ferrari(10), Tiziana Fanelli(9), Giovanni Barosi(9), Silvia Salmoiraghi(6), Giorgia Sacchi(6), Michele Cea(6)