Brian D. O’Donovan

Boston University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.0kcitations35works17.42yr avg
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Research Topics

Genomics and Phylogenetic Studies(7), RNA and protein synthesis mechanisms(6), Bacterial Infections and Vaccines(6), Monoclonal and Polyclonal Antibodies Research(6), Mycobacterium research and diagnosis(6)

Publications35 total

P-1784. Analytical Validation of a Metagenomic Next Generation Sequencing (mNGS) Test for Agnostic Detection of Microbial Organisms in CNS Infections
Open Forum Infectious Diseases·2026Open Access
Analysis of Metagenomic Next‐Generation Sequencing Data Obtained from Clinical Samples
2025
Broad, Agnostic Pathogen Detection through Metagenomic Next Generation Sequencing (mNGS) of Cerebrospinal Fluid (CSF) to Diagnose CNS Infections (P7-10.007)
Neurology·2025
Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections
Nature Medicine·2024· 101 citedOpen Access
Clinical impact of metagenomic next-generation sequencing testing on cerebrospinal fluid in a pediatric cohort with suspected central nervous system infections
Journal of the Pediatric Infectious Diseases Society·2024Open Access
Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity
Journal of Clinical Investigation·2024· 35 citedOpen Access
Pathogen Detection and Associated Patient Characteristics from Clinical Metagenomic Nextgeneration Sequencing Testing for Neurological Infections (S25.002)
Neurology·2024
Metagenomic next-generation sequencing of cerebrospinal fluid for diagnosis of central nervous system infections: 7-year performance of a clinically validated test
2024· 3 citedOpen Access
Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy
2023· 7 citedOpen Access
DeRisi Lab Phage Immunoprecipitation Sequencing (PhIP-Seq) v1
2023· 1 citedOpen Access
Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis
Nature Medicine·2021Open Access
Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries
Proceedings of the National Academy of Sciences·2020· 54 citedOpen Access
Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries
2020· 4 citedOpen Access
High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display
Brain Communications·2020· 64 citedOpen Access
Pan-viral serology implicates enteroviruses in acute flaccid myelitis
Nature Medicine·2019· 127 citedOpen Access
Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis
New England Journal of Medicine·2019· 253 citedOpen Access
Serological and metagenomic interrogation of cerebrospinal fluid implicates enteroviruses in pediatric acute flaccid myelitis
2019· 3 citedOpen Access
Exploration of Anti-Yo and Anti-Hu paraneoplastic neurological disorders by PhIP-Seq reveals a highly restricted pattern of antibody epitopes
2018· 9 citedOpen Access
Misinterpretation of Study Data—Reply
JAMA Neurology·2018Open Access
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing
JAMA Neurology·2018· 309 citedOpen Access
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Frequent Co-authors

Michael R. Wilson(21), Joseph L. DeRisi(21), Kelsey C. Zorn(11), Charles Y. Chiu(10), Steve Miller(9), Emily Crawford(8), Lillian M. Khan(8), Eric D. Chow(7), Hannah A. Sample(7), Mark Gorman(5), Debarko Banerji(5), Charles Langelier(5), Ariane Soldatos(5), Caleigh Mandel‐Brehm(5), Stephen L. Hauser(5), Timothy M. Blicharz(5), Sara E. Vazquez(4), Patrick Benoit(4), Noah Brazer(4), Venice Servellita(4)