Dezider Grünberger

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index7.8kcitations154works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(70), RNA and protein synthesis mechanisms(40), RNA modifications and cancer(26), Carcinogens and Genotoxicity Assessment(22), DNA Repair Mechanisms(20)

Publications154 total

Conformational Changes in Nucleic Acids Modified by Chemical Carcinogens
2019· 10 cited
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
PubMed·1999· 375 cited
Caffeic acid phenethyl ester profoundly modifies protein synthesis profile in type 5 adenovirus-transformed cloned rat embryo fibroblast cells
International Journal of Oncology·1997· 16 cited
Caffeic acid phenethyl ester stimulates human antioxidant response element-mediated expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene.
PubMed·1997· 59 cited
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
Proceedings of the National Academy of Sciences·1996· 1.1k citedOpen Access
ChemInform Abstract: Hydroxylated Aromatic Inhibitors of HIV‐1 Integrase.
ChemInform·1996
Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-<i>O</i>-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells
Carcinogenesis·1996· 133 citedOpen Access
Hydroxylated Aromatic Inhibitors of HIV-1 Integrase
Journal of Medicinal Chemistry·1995· 173 citedOpen Access
Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells.
PubMed·1995· 176 cited
Solution Conformation of the N-(Deoxyguanosin-8-yl)aminofluorene Adduct opposite Deoxyinosine and Deoxyguanosine in DNA by NMR and Computational Characterization
Chemical Research in Toxicology·1995· 17 cited
Caffeic acid phenethyl ester inhibits proliferation of human keratinocytes and interferes with the EGF regulation of ornithine decarboxylase.
PubMed·1995· 54 cited
EXPRESSION OF THE TRANSFORMED PHENOTYPE INDUCED BY DIVERSE ACTING VIRAL ONCOGENES MEDIATES SENSITIVITY TO GROWTH SUPPRESSION INDUCED BY CAFFEIC ACID PHENETHYL ESTER (CAPE)
International Journal of Oncology·1994· 13 cited
Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression.
PubMed·1994· 74 cited
Mutation and repair induced by the carcinogen 2-(Hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA
Chemical Research in Toxicology·1994· 50 cited
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro.
Journal of Clinical Investigation·1994· 127 citedOpen Access
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.
PubMed·1993· 168 cited
Splicing Mutants and Their Second-Site Suppressors at the Dihydrofolate Reductase Locus in Chinese Hamster Ovary Cells
Molecular and Cellular Biology·1993· 76 citedOpen Access
Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester.
PubMed·1993· 198 cited
A mutational hot spot induced by <i>N</i>-hydroxy-aminofluorene in dihydrofolate reductase mutants of Chinese hamster ovary cells
Carcinogenesis·1993· 16 cited
DNA strand-specific repair of (+-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene adducts in the hamster dihydrofolate reductase gene.
Proceedings of the National Academy of Sciences·1992· 27 citedOpen Access
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Frequent Co-authors

I. Bernard Weinstein(14), Adelaide M. Carothers(9), Regina M. Santella(8), Peter Pulkrabek(5), I. Bernard Weinstein(4), Steven H. Blobstein(4), Steven Leffler(4), Krystyna Frenkel(3), Miriam C. Poirier(3), Stuart H. Yuspa(3), Gail Urlaub(3), Lawrence A. Chasin(3), Brian E. Hingerty(3), Suse Broyde(3), Terrence R. Burke(2), Brett C. Singer(2), Ramesh Bhimani(2), Mou‐Tuan Huang(2), Koji Nakanishi(2), Nobuo Furutachi(2)