Margaret R. MacDonald

Rockefeller University — United States

Medicine · Health Sciences

44h-index6.7kcitations90works5.72yr avg
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Research Topics

Mosquito-borne diseases and control(37), interferon and immune responses(27), Viral Infections and Vectors(25), Viral Infections and Immunology Research(9), SARS-CoV-2 and COVID-19 Research(8)

Publications90 total

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
UNC Libraries·2025Open Access
An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma
2025Open Access
Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephalitis in seven new cohorts
2025Open Access
Mitochondrial hyperactivity and reactive oxygen species drive innate immunity to the yellow fever virus-17D live-attenuated vaccine
PLoS Pathogens·2025· 4 citedOpen Access
Auto-Abs neutralizing type I IFNs in patients with severe Powassan, Usutu, or Ross River virus disease
The Journal of Experimental Medicine·2024· 20 citedOpen Access
Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalitis in ∼10% of patients
The Journal of Experimental Medicine·2024· 27 citedOpen Access
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
PLoS Biology·2024· 12 citedOpen Access
Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
2024· 3 citedOpen Access
A reporter virus particle seroneutralization assay for tick‐borne encephalitis virus overcomes ELISA limitations
Journal of Medical Virology·2024· 3 citedOpen Access
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses
Cell Reports·2024· 1 citedOpen Access
Prevalence of Powassan Virus Seropositivity Among People with History of Lyme Disease and Non-Lyme Community Controls in the Northeastern United States
Vector-Borne and Zoonotic Diseases·2024· 3 citedOpen Access
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
2024· 1 citedOpen Access
A reporter virus particle seroneutralization assay for tick-borne encephalitis virus overcomes ELISA limitations
2024Open Access
Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies
Proceedings of the National Academy of Sciences·2023· 4 citedOpen Access
Human FcγRIIIa activation on splenic macrophages drives dengue pathogenesis in mice
Nature Microbiology·2023· 23 citedOpen Access
Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients
The Journal of Experimental Medicine·2023· 97 citedOpen Access
Characterization of Live-Attenuated Powassan Virus Vaccine Candidates Identifies an Efficacious Prime-Boost Strategy for Mitigating Powassan Virus Disease in a Murine Model
Vaccines·2023· 17 citedOpen Access
Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
Cell·2023· 100 citedOpen Access
Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease
2022· 4 citedOpen Access
Sindbis Macrodomain Poly-ADP-Ribose Hydrolase Activity Is Important for Viral RNA Synthesis
Journal of Virology·2022· 9 citedOpen Access
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Frequent Co-authors

Charles M. Rice(33), William M. Schneider(9), Hans-Heinrich Hoffmann(9), Eleftherios Michailidis(7), Avery Peace(7), Melody M. H. Li(7), Jérémie Le Pen(6), John T. Poirier(6), Joseph M. Luna(5), Francisco J. Sánchez‐Rivera(5), Alison W. Ashbrook(5), Inna Ricardo-Lax(5), Scott W. Lowe(5), Xianfang Wu(5), Davide F. Robbiani(5), Leonia Bozzacco(5), Anna Gazumyan(5), Michel C. Nussenzweig(5), Andrew A. Leal(4), Ansgar F. Stenzel(4)