Alison W. Ashbrook

Rockefeller University — United States

Medicine · Health Sciences

23h-index4.2kcitations36works14.72yr avg
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Research Topics

Mosquito-borne diseases and control(16), Viral Infections and Vectors(11), SARS-CoV-2 and COVID-19 Research(9), interferon and immune responses(7), Liver Disease Diagnosis and Treatment(4)

Publications36 total

Mitochondrial hyperactivity and reactive oxygen species drive innate immunity to the yellow fever virus-17D live-attenuated vaccine
PLoS Pathogens·2025· 4 citedOpen Access
Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase
Nature·2024· 35 cited
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection ameliorates secondary influenza A virus disease
Immunity·2024· 33 citedOpen Access
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
PLoS Biology·2024· 12 citedOpen Access
Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
2024· 3 citedOpen Access
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
2024· 1 citedOpen Access
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection
2023· 4 citedOpen Access
Characterization of Live-Attenuated Powassan Virus Vaccine Candidates Identifies an Efficacious Prime-Boost Strategy for Mitigating Powassan Virus Disease in a Murine Model
Vaccines·2023· 17 citedOpen Access
Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
Cell Reports·2022· 30 citedOpen Access
IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease
Journal of Hepatology·2022· 117 citedOpen Access
Sindbis Macrodomain Poly-ADP-Ribose Hydrolase Activity Is Important for Viral RNA Synthesis
Journal of Virology·2022· 9 citedOpen Access
Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals
mSphere·2021· 28 citedOpen Access
Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
2021· 4 citedOpen Access
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Cell Host & Microbe·2020· 168 citedOpen Access
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
Cell·2020· 429 citedOpen Access
Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice
2020· 2 citedOpen Access
Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus
UNC Libraries·2020· 2 citedOpen Access
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks
2020· 52 citedOpen Access
Defining the proteolytic landscape during enterovirus infection
PLoS Pathogens·2020· 46 citedOpen Access
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020· 36 citedOpen Access
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Frequent Co-authors

Charles M. Rice(23), Hans-Heinrich Hoffmann(13), Eleftherios Michailidis(11), Margaret R. MacDonald(11), Joseph M. Luna(9), Inna Ricardo-Lax(9), Terence S. Dermody(9), William M. Schneider(8), Jérémie Le Pen(8), Ansgar F. Stenzel(8), Francisco J. Sánchez‐Rivera(6), Avery Peace(6), John T. Poirier(6), Laurie A. Silva(6), Corrine Quirk(6), Brandon S. Razooky(6), Julie M. Fox(5), Thomas E. Morrison(5), Luis Chiriboga(5), Andrew A. Leal(4)