Gyun Min Lee

Korea Advanced Institute of Science and Technology — South Korea

Biochemistry, Genetics and Molecular Biology · Life Sciences

53h-index19.0kcitations303works4.22yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(234), Protein purification and stability(79), Virus-based gene therapy research(73), CRISPR and Genetic Engineering(71), Monoclonal and Polyclonal Antibodies Research(58)

Publications299 total

CRISPR screen-based mammalian cell engineering for complex biotherapeutics
Trends in biotechnology·2025
Genome-wide CRISPR screening identifies genes in recombinant human embryonic kidney 293 cells for increased ammonia resistance
Metabolic Engineering·2025
Recombinase-Mediated Cassette Exchange-Based CRISPR Activation Screening Identifies Hyperosmotic Stress-Resistant Genes in Chinese Hamster Ovary Cells
ACS Synthetic Biology·2025
Improving recombinant antibody production using FcBAR: An in situ approach to detect and amplify protein-protein interactions
Metabolic Engineering·2025· 3 citedOpen Access
Improving Recombinant Antibody Production Using FcBAR: An In Situ Approach to Detect and Amplify Protein-Protein Interactions
2025Open Access
Comprehensive genome-scale CRISPR knockout screening of CHO cells
Scientific Data·2025· 2 citedOpen Access
Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells
Nature Metabolism·2025· 15 citedOpen Access
Knockout of Pro‐Apoptotic <i>BAX</i> and <i>BAK1</i> Genes in HEK293T Cells Enhances Adeno‐Associated Virus (AAV) Production: AAV2 and AAV9
Biotechnology Journal·2025· 4 citedOpen Access
Unraveling productivity-enhancing genes in Chinese hamster ovary cells via CRISPR activation screening using recombinase-mediated cassette exchange system
Metabolic Engineering·2024· 4 citedOpen Access
Antiapoptosis Engineering for Improved Protein Production from CHO Cells
Methods in molecular biology·2024
Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells
2024· 2 citedOpen Access
SiMPl‐GS: Advancing Cell Line Development via Synthetic Selection Marker for Next‐Generation Biopharmaceutical Production
Advanced Science·2024· 4 citedOpen Access
Sialyllactose supplementation enhances sialylation of Fc-fusion glycoprotein in recombinant Chinese hamster ovary cell culture
Journal of Biotechnology·2024· 3 citedOpen Access
Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
Biotechnology and Bioprocess Engineering·2024· 1 citedOpen Access
Enhancing the production of adeno‐associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design‐of‐experiment optimization of triple plasmid ratio
Biotechnology Journal·2024· 16 citedOpen Access
Effects of autophagy-inhibiting chemicals on sialylation of Fc-fusion glycoprotein in recombinant CHO cells
Applied Microbiology and Biotechnology·2024· 7 citedOpen Access
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP–SETDB1 Complex for Enhancing Difficult-to-Express Protein Production
ACS Synthetic Biology·2024· 11 cited
Genome‐wide CRISPR/Cas9 knockout screening to mitigate cell growth inhibition induced by histone deacetylase inhibitors in recombinant CHO cells
Biotechnology and Bioengineering·2023· 6 citedOpen Access
Enhancing the production of recombinant human TGF‐β1 through an understanding of TGF‐β1 synthesis, signaling, and endocytosis in CHO cells
Biotechnology Journal·2023· 4 cited
In vitro induction of in vivo–relevant stellate astrocytes in 3D brain-derived, decellularized extracellular matrices
Acta Biomaterialia·2023· 4 cited
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Frequent Co-authors

Helene Faustrup Kildegaard(10), Lise Marie Grav(8), Gou Young Koh(7), Jae Seong Lee(7), Nathan E. Lewis(6), No Soo Kim(5), Lasse Ebdrup Pedersen(5), Yeon‐Gu Kim(4), Chung‐Hyun Cho(4), Kyung-Tae Kim(4), Han-Ho Choi(4), Sung Hyun Kim(4), Sung Kwan Yoon(4), Yun Hee Sung(4), Mikael Rørdam Andersen(4), Jee Yon Kim(3), Richard A. Kammerer(3), Sang Jick Kim(3), Thomas Beuchert Kallehauge(3), Anders Holmgaard Hansen(3)