Thomas Amann

Novo Nordisk Foundation — Denmark

Medicine · Health Sciences

17h-index1.8kcitations64works0.02yr avg
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Research Topics

Liver physiology and pathology(15), Cancer, Hypoxia, and Metabolism(11), Liver Disease Diagnosis and Treatment(10), Fibroblast Growth Factor Research(9), Metabolism, Diabetes, and Cancer(8)

Publications64 total

Identification of novel miRNA targets in CHO cell lines and characterization of their impact on protein N-glycosylation
2022· 4 citedOpen Access
Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms
Biotechnology and Bioengineering·2019· 46 citedOpen Access
Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles
Metabolic Engineering·2018· 55 cited
Die Auswirkungen der Digitalisierung auf den Berufsstand des Wirtschaftsprüfers
Publication Server of the Catholic University Eichstätt-Ingolstadt (Catholic University of Eichstätt-Ingolstadt)·2018
CRISPR/Cas9‐Multiplexed Editing of Chinese Hamster Ovary B4Gal‐T1, 2, 3, and 4 Tailors <i>N</i>‐Glycan Profiles of Therapeutics and Secreted Host Cell Proteins
Biotechnology Journal·2018· 36 citedOpen Access
Targeting miRNAs with CRISPR/Cas9 to Improve Recombinant Protein Production of CHO Cells
Methods in molecular biology·2018· 13 cited
Design of Optimal CHO Protein N-glycosylation Profiles
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)·2018Open Access
Humanizing recombinant glycoproteins from Chinese hamster ovary cells
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)·2017Open Access
Deutsche Prüfstelle für Rechnungslegung e.V. (DPR)
2017
CHO glyco-engineering using CRISPR/Cas9 multiplexing for protein production with homogeneous N-glycan profiles
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)·2017Open Access
Exploring the capabilities of fluorometric online monitoring on chinese hamster ovary cell cultivations producing a monoclonal antibody
Biotechnology Progress·2016· 14 cited
Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma
PLoS Computational Biology·2015· 26 citedOpen Access
Fibroblast growth factor 7 inhibits hepatic steatosis, inflammation and fibrosis in murine models of on non-alcoholic steatohepatitis
Zeitschrift für Gastroenterologie·2015
Loss of Anterior Gradient-2 expression is an independent prognostic factor in colorectal carcinomas
European Journal of Cancer·2014· 22 cited
Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury
Zeitschrift für Gastroenterologie·2014· 1 cited
<i>In vivo</i>siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates Concanavalin A-induced acute liver injury in mice
Disease Models & Mechanisms·2014· 16 citedOpen Access
Software-Safety für Embedded-Systeme steht ganz oben
IT-Szene München·2013
Targeting Melanoma Metastasis and Immunosuppression with a New Mode of Melanoma Inhibitory Activity (MIA) Protein Inhibition
PLoS ONE·2012· 24 citedOpen Access
Adiponectin reduces connective tissue growth factor in human hepatocytes which is already induced in non-fibrotic non-alcoholic steatohepatitis
Experimental and Molecular Pathology·2011· 23 cited
Analysis of a promoter polymorphism of the GLUT1 gene in patients with hepatocellular carcinoma
Molecular Membrane Biology·2011· 17 cited
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Frequent Co-authors

Claus Hellerbrand(27), Anja‐Katrin Bosserhoff(20), Jürgen Schölmerich(8), Thomas S. Weiß(7), Thilo Spruß(7), Ulrike Maegdefrau(5), Marcus Mühlbauer(5), Helene Faustrup Kildegaard(5), D Valletta(5), F Bataille(4), Anders Holmgaard Hansen(4), Mikael Rørdam Andersen(4), A. Hartmann(4), B Czech(4), Oliver Stoeltzing(3), Peter J. Oefner(3), Stefan Kol(3), Gyun Min Lee(3), Georgi Kirovski(3), Christina Warnecke(2)