Stefan Kol

Novo Nordisk Foundation — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.5kcitations49works8.52yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(19), Monoclonal and Polyclonal Antibodies Research(8), ATP Synthase and ATPases Research(8), CRISPR and Genetic Engineering(7), Protein purification and stability(7)

Publications49 total

Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells
Nature Metabolism·2025· 15 citedOpen Access
Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells
2024· 2 citedOpen Access
In situ detection of protein interactions for recombinant therapeutic enzymes
Biotechnology and Bioengineering·2020· 5 citedOpen Access
In situ detection of protein interactions for recombinant therapeutic enzymes
2020Open Access
In situ detection of protein interactions for recombinant therapeutic enzymes
2020· 1 citedOpen Access
Multiplex secretome engineering enhances recombinant protein production and purity
Nature Communications·2020· 119 citedOpen Access
Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla
Cell Host & Microbe·2019· 9 citedOpen Access
Evolution-guided engineering of small-molecule biosensors
Nucleic Acids Research·2019· 136 citedOpen Access
Multiplex secretome engineering enhances recombinant protein production and purity
2019· 16 citedOpen Access
Evolution-guided engineering of small-molecule biosensors
2019· 11 citedOpen Access
Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla
Cell Host & Microbe·2019· 84 citedOpen Access
Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles
Metabolic Engineering·2018· 55 cited
Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence
Nature Communications·2018· 66 citedOpen Access
CRISPR/Cas9‐Multiplexed Editing of Chinese Hamster Ovary B4Gal‐T1, 2, 3, and 4 Tailors <i>N</i>‐Glycan Profiles of Therapeutics and Secreted Host Cell Proteins
Biotechnology Journal·2018· 36 citedOpen Access
Engineering CHO cells for the production of "Hard-To-Produce" proteins
2018
Elimination of the Warburg effect in Chinese hamster ovary (CHO) cells improves cell phenotype as a protein production platform
2018
Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity
Biotechnology Journal·2017· 32 citedOpen Access
The CYP79A1 catalyzed conversion of tyrosine to (E)-p-hydroxyphenylacetaldoxime unravelled using an improved method for homology modeling
Phytochemistry·2017· 11 cited
Droplet microfluidics and split-GFP complementation enable selection of Chinese hamster ovary cells with high specific productivity of therapeutic glycoproteins
2017
Humanizing recombinant glycoproteins from Chinese hamster ovary cells
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)·2017Open Access
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Frequent Co-authors

Helene Faustrup Kildegaard(15), Gyun Min Lee(12), Anders Holmgaard Hansen(11), Nathan E. Lewis(10), Arnold J. M. Driessen(9), Björn G. Voldborg(9), L. Tresaugues(9), M.I. Siponen(9), C.H. Arrowsmith(9), H. Berglund(9), C. Bountra(9), A.M. Edwards(9), S. Flodin(9), S. Gräslund(9), M. Hammarstrom(9), T. Karlberg(9), T. Kotenyova(9), E. Kouznetsova(9), M. Moche(9), E. Wahlberg(9)