Gary Bridson

Concert Pharmaceuticals (United States) — United States

Medicine · Health Sciences

6h-index299citations9works0.02yr avg
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Research Topics

HIV/AIDS drug development and treatment(3), Chemical Reactions and Isotopes(3), HIV Research and Treatment(2), Hepatitis C virus research(2), Pharmacogenetics and Drug Metabolism(2)

Publications9 total

Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
Journal of Pharmacology and Experimental Therapeutics·2017· 73 citedOpen Access
Altering Metabolic Profiles of Drugs by Precision Deuteration: Reducing Mechanism-Based Inhibition of CYP2D6 by Paroxetine
Journal of Pharmacology and Experimental Therapeutics·2015· 55 cited
Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury
Journal of Neurotrauma·2015· 19 cited
Quantitative analyses of CTP-499 and five major metabolites by core-structure analysis
Journal of Chromatography B·2014· 14 cited
Identification and structural elucidation of <i>in vitro</i> metabolites of atazanavir by HPLC and tandem mass spectrometry
Journal of Mass Spectrometry·2013· 5 cited
Design and synthesis of deuterated boceprevir analogs with enhanced pharmacokinetic properties
Journal of Labelled Compounds and Radiopharmaceuticals·2011· 15 cited
The effect of CTP-347 on CYP2D6-mediated tamoxifen metabolism
Journal of Clinical Oncology·2008
In Vitro–In Vivo Correlation on Delivery of Drug Candidates to Articular Cartilage
Pharmaceutical Research·2008· 5 cited
Metabolism of Amprenavir in Liver Microsomes: Role of CYP3A4 Inhibition for Drug Interactions
Journal of Pharmaceutical Sciences·1998· 113 cited

Frequent Co-authors

Roger D. Tung(6), Scott L. Harbeson(5), Vinita Uttamsingh(5), Julie F. Liu(3), Richard Gallegos(3), Changfu Cheng(3), Robert E. Zelle(3), Adam J. Morgan(2), Sophia Nguyen(2), Lijun Wu(2), Virginia Braman(2), David S. Wells(2), Philip B. Graham(2), Caroline J. Decker(1), Leena M. Laitinen(1), Scott A. Raybuck(1), Pravin Chaturvedi(1), Ara M. Aslanian(1), Christopher L. Brummel(1), Lana Pilja(1)