Robert E. Zelle

Concert Pharmaceuticals (United States) — United States

Chemistry · Physical Sciences

13h-index1.0kcitations28works0.02yr avg
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Research Topics

Asymmetric Synthesis and Catalysis(5), Chemical Synthesis and Analysis(4), Asymmetric Hydrogenation and Catalysis(4), Carbohydrate Chemistry and Synthesis(3), Synthetic Organic Chemistry Methods(3)

Publications28 total

Altering Metabolic Profiles of Drugs by Precision Deuteration: Reducing Mechanism-Based Inhibition of CYP2D6 by Paroxetine
Journal of Pharmacology and Experimental Therapeutics·2015· 55 cited
Identification and structural elucidation of <i>in vitro</i> metabolites of atazanavir by HPLC and tandem mass spectrometry
Journal of Mass Spectrometry·2013· 5 cited
The effect of CTP-347 on CYP2D6-mediated tamoxifen metabolism
Journal of Clinical Oncology·2008
Cellular and biochemical characterization of VX-710 as a chemosensitizer
Anti-Cancer Drugs·1997· 130 cited
Preclinical profile of VX-710, a novel MDR chemosensitizer
Anti-Cancer Drugs·1994
Synthesis and pharmacological characterization of ABT-200: a putative novel antidepressant combining potent α-2 antagonism with moderate NE uptake inhibition
Bioorganic & Medicinal Chemistry Letters·1994· 19 cited
ChemInform Abstract: Resolution of 4‐Phenyl‐2‐pyrrolidinone: A Versatile Synthetic Intermediate.
ChemInform·1992
ChemInform Abstract: A Simple, High‐Yielding Method for the Methylenation of Catechols.
ChemInform·1992
A simple, high-yielding method for the methylenation of catechols
Tetrahedron Letters·1991· 33 cited
Resolution of 4-Phenyl-2-pyrrolidinone: A Versatile Synthetic Intermediate
Synthesis·1991· 28 cited
ChemInform Abstract: Total Synthesis of Zincophorin.
ChemInform·1988
Total synthesis of zincophorin
Journal of the American Chemical Society·1988· 130 cited
ChemInform Abstract: A Systematic Degradation of Zincophorin (I): Stereoselective Synthesis of the C17‐C25 Fragment.
ChemInform·1987
ChemInform Abstract: Total Synthesis of Zincophorin.
ChemInform·1987
The total synthesis of zincophorin
Journal of the American Chemical Society·1987· 42 cited
ChemInform Abstract: Convergent, Enantiospecific Total Synthesis of the Hypocholesterolemic Agent (+)‐Compactin.
ChemInform·1987
A systematic degradation of zincophorin: a stereoselective synthesis of the C17-C25 fragment
The Journal of Organic Chemistry·1986· 38 cited
ChemInform Abstract: On the Communication of Chirality from Furanose and Pyranose Rings to Monosaccharide Side Chains: Anomalous Results in the Glucose Series.
Chemischer Informationsdienst·1986
Convergent, enantiospecific total synthesis of the hypocholesterolemic agent (+)-compactin
Journal of the American Chemical Society·1986· 66 cited
On the communication of chirality from furanose and pyranose rings to monosaccharide side chains: anomalous results in the glucose series
Tetrahedron·1986· 95 cited
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Frequent Co-authors

Paul A. Grieco(8), Michael P. DeNinno(8), Samuel J. Danishefsky(7), Harold G. Selnick(6), R. LIS(4), John M. Finn(3), Richard Gallegos(3), Scott L. Harbeson(3), Gary Bridson(3), Roger D. Tung(3), Daniel L. Flynn(2), Ursula A. Germann(2), Valerie S. Mason(2), John P. Duffy(2), Vincent Galullo(2), David M. Armistead(2), Jeffrey O. Saunders(2), Joshua Boger(2), Matthew W. Harding(2), Gary B. Phillips(2)