Changfu Cheng

First People's Hospital of Yunnan Province — China

Chemistry · Physical Sciences

10h-index686citations17works0.02yr avg
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Research Topics

Mass Spectrometry Techniques and Applications(5), Analytical Chemistry and Chromatography(4), Chemical Reactions and Isotopes(4), Pharmacogenetics and Drug Metabolism(3), Metabolomics and Mass Spectrometry Studies(3)

Publications17 total

Ryanodine receptor (RYR) mutational status correlates with tumor mutational burden, age and smoking status and stratifies non-small cell lung cancer patient prognosis
Translational Cancer Research·2022· 8 citedOpen Access
Issue Information
Clinical Pharmacology in Drug Development·2016Open Access
A First‐in‐Patient, Multicenter, Double‐Blind, 2‐Arm, Placebo‐Controlled, Randomized Safety and Tolerability Study of a Novel Oral Drug Candidate, CTP‐499, in Chronic Kidney Disease
Clinical Pharmacology in Drug Development·2015· 25 citedOpen Access
Altering Metabolic Profiles of Drugs by Precision Deuteration: Reducing Mechanism-Based Inhibition of CYP2D6 by Paroxetine
Journal of Pharmacology and Experimental Therapeutics·2015· 55 cited
Identification of CTP-499 metabolites in human plasma and urine
Journal of Analytical & Bioanalytical Techniques·2014
Quantitative analyses of CTP-499 and five major metabolites by core-structure analysis
Journal of Chromatography B·2014· 14 cited
Revealing the metabolic sites of atazanavir in human by parallel administrations of D‐atazanavir analogs
Journal of Mass Spectrometry·2013· 1 cited
Identification and structural elucidation of <i>in vitro</i> metabolites of atazanavir by HPLC and tandem mass spectrometry
Journal of Mass Spectrometry·2013· 5 cited
Abstract 3357: CTP-221, a deuterated S-enantiomer of lenalidomide, is greatly stabilized to epimerization and results in a more desirable pharmacokinetic profile than racemic lenalidomide.
Cancer Research·2013· 11 cited
A Randomized Phase I Evaluation of CTP‐499, a Novel Deuterium‐Containing Drug Candidate for Diabetic Nephropathy
Clinical Pharmacology in Drug Development·2013· 29 cited
ChemInform Abstract: Applications and Mechanisms of Charge‐Remote Fragmentation
ChemInform·2001
Applications and mechanisms of charge-remote fragmentation
Mass Spectrometry Reviews·2000· 263 cited
Applications and mechanisms of charge‐remote fragmentation
Mass Spectrometry Reviews·2000· 6 cited
Complete Structural Elucidation of Triacylglycerols by Tandem Sector Mass Spectrometry
Analytical Chemistry·1998· 178 cited
Charge-remote fragmentations are energy-dependent processes
Journal of the American Society for Mass Spectrometry·1998· 51 cited
Fragmentation mechanisms of oxofatty acids via high-energy collisional activation
Journal of the American Society for Mass Spectrometry·1998· 16 cited
Structural determination of oxofatty acids by charge-remote fragmentations
Journal of the American Society for Mass Spectrometry·1998· 24 cited

Frequent Co-authors

Michael L. Gross(7), Virginia Braman(5), Roger D. Tung(4), Richard Gallegos(3), Scott L. Harbeson(3), Gary Bridson(3), Philip B. Graham(3), LuAnn Sabounjian(3), James E. Shipley(3), Lijun Wu(3), Ernst Pittenauer(2), Vinita Uttamsingh(2), Julie F. Liu(2), Robert E. Zelle(2), Julie Liu(2), Joel Neutel(2), Lijun Wu(2), David S. Wells(1), David J. Turnquist(1), Mark Harnett(1)