Hang‐zi Chen

Xiamen University — China

Neuroscience · Life Sciences

28h-index3.7kcitations51works13.62yr avg
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Research Topics

Nuclear Receptors and Signaling(30), Macrophage Migration Inhibitory Factor(21), Autophagy in Disease and Therapy(8), MicroRNA in disease regulation(6), Epigenetics and DNA Methylation(6)

Publications51 total

Disruption of heme homeostasis by nuclear receptor Nur77 induces pyroptosis through granzyme B-dependent GSDMC cleavage
Signal Transduction and Targeted Therapy·2025Open Access
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science·2025· 1 citedOpen Access
Activation of AKT via a dual mechanism enhances the susceptibility of melanoma cells to glucose deprivation
Cell Death and Disease·2025· 1 citedOpen Access
cGAS activation converges with intracellular acidification to promote STING aggregation and pyroptosis in tumor models
Journal of Clinical Investigation·2025· 8 citedOpen Access
Full-length GSDME mediates pyroptosis independent from cleavage
Nature Cell Biology·2024· 58 cited
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P
Cell Research·2023· 89 citedOpen Access
Table S1 from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Supplementary methods from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Supplementary Figures from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Table S1 from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Supplementary Figures from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Data from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Supplementary methods from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Data from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
2023Open Access
Data from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
Supplementary Materials and Methods from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
Supplementary Figures 1-5 from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
Data from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
Supplementary Materials and Methods from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
Supplementary Figures 1-5 from A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 <i>In vivo</i> and <i>In vitro</i>
2023Open Access
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Frequent Co-authors

Qiao Wu(32), Qi-Tao Chen(18), Jianping He(17), Peipei Hou(15), Luming Yao(15), Yan-yan Zhan(14), Pengbo Yang(13), Qiao Wu(13), Kun‐Yi Chien(11), Xiaoyu Sun(11), Hongkui Zhang(10), Pei‐Qiang Huang(10), Weijia Wang(10), Tianwei Lin(9), Wenbin Hong(9), Ying-Ping Li(9), Xin‐Dong Jiang(9), Qiu-Wan Wu(9), Allison J. Cowin(9), Yuan-li Ai(8)