Wenbin Hong

Xiamen University — China

Immunology and Microbiology · Life Sciences

7h-index390citations21works2.92yr avg
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Research Topics

Macrophage Migration Inhibitory Factor(7), Nuclear Receptors and Signaling(7), Liver physiology and pathology(3), Parasites and Host Interactions(2), Inflammasome and immune disorders(2)

Publications21 total

Disruption of heme homeostasis by nuclear receptor Nur77 induces pyroptosis through granzyme B-dependent GSDMC cleavage
Signal Transduction and Targeted Therapy·2025Open Access
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science·2025· 1 citedOpen Access
Structure-Based Design and Optimization of Bi-Aryl Amide Derivatives as Nur77 Ligands for Nur77-Bcl-2-Dependent Apoptotic Cancer Therapy
Journal of Medicinal Chemistry·2025
Spatio-Temporal Evolution Characteristics of Soil Erosion Disasters Based on the RUSLE Model
2025
Activation of AKT via a dual mechanism enhances the susceptibility of melanoma cells to glucose deprivation
Cell Death and Disease·2025· 1 citedOpen Access
cGAS activation converges with intracellular acidification to promote STING aggregation and pyroptosis in tumor models
Journal of Clinical Investigation·2025· 8 citedOpen Access
Taurine as a supplement for treating type II diabetes mellitus with metformin and DPP4 inhibitor
Scientific Reports·2025· 2 citedOpen Access
The structural basis of TRIM25-mediated regulation of RIG-I
Journal of Biological Chemistry·2025· 5 citedOpen Access
Discovery of a novel exceptionally potent and orally active Nur77 ligand NB1 with a distinct binding mode for cancer therapy
Acta Pharmaceutica Sinica B·2024· 7 citedOpen Access
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene
Bioorganic Chemistry·2024· 5 cited
Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway
European Journal of Pharmacology·2023· 11 cited
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77
Bioorganic Chemistry·2023· 7 citedOpen Access
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P
Cell Research·2023· 89 citedOpen Access
Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein
Cell chemical biology·2023· 7 citedOpen Access
HK1 from hepatic stellate cell–derived extracellular vesicles promotes progression of hepatocellular carcinoma
Nature Metabolism·2022· 108 citedOpen Access
Structural insights into the redox regulation of Oncomelania hupensis TRP14 and its potential role in the snail host response to parasite invasion
Fish & Shellfish Immunology·2022· 1 cited
A secreted MIF homologue from Trichinella spiralis binds to and interacts with host monocytes
Acta Tropica·2022· 5 cited
Intercellular Communication in the Progression from Fibrosis to HCC by Ectosomal HK1-Induced TGF-β Secretion
SSRN Electronic Journal·2021Open Access
Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression
Proceedings of the National Academy of Sciences·2020· 133 citedOpen Access
Clinical analysis on 96 cases of non-typical measles in adults
2011
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Frequent Co-authors

Tianwei Lin(10), Hang‐zi Chen(9), Qiao Wu(7), Liu-zheng Wu(6), Qi-Tao Chen(5), Xueqin Chen(5), Cui-yu Ju(4), Ya‐ying Huang(4), Songqing Wang(4), Peipei Hou(3), Xianming Deng(3), Yuan-li Ai(3), Hongyu Hu(3), Fu-Nan Li(3), Meijuan Fang(3), Tianyichen Xiao(3), Zhiming Su(3), Pengbo Yang(2), Zhiyuan Zhang(2), Qiaoling Huang(2)