Mandy Madiredjo

The Netherlands Cancer Institute — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index4.0kcitations8works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(3), Ubiquitin and proteasome pathways(2), HIV Research and Treatment(1), DNA Repair Mechanisms(1), Advanced biosensing and bioanalysis techniques(1)

Publications8 total

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation
Oncotarget·2015· 69 citedOpen Access
A Large Scale shRNA Barcode Screen Identifies the Circadian Clock Component ARNTL as Putative Regulator of the p53 Tumor Suppressor Pathway
PLoS ONE·2009· 141 citedOpen Access
A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer
Cancer Cell·2007· 1.6k citedOpen Access
The ubiquitin-specific protease USP28 is required for MYC stability
Nature Cell Biology·2007· 480 cited
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
Nature Chemical Biology·2006· 187 citedOpen Access
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
Nature Cell Biology·2004· 1.1k citedOpen Access
Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition
Journal of Virology·2004· 424 citedOpen Access
Functional Identification of Cancer-relevant Genes through Large-Scale RNA Interference Screens in Mammalian Cells
Cold Spring Harbor Symposia on Quantitative Biology·2004· 16 citedOpen Access

Frequent Co-authors

René Bernards(8), Roderick L. Beijersbergen(7), Katrien Berns(4), Jasper Mullenders(4), Thijn R. Brummelkamp(4), E. Marielle Hijmans(3), Arno Velds(3), Ron Kerkhoven(3), Armida W. M. Fabius(3), Mike Heimerikx(2), Hugo M. Horlings(1), Bryan T. Hennessy(1), Karin Beelen(1), Sabine C. Linn(1), Ana M. González-Angulo(1), Katherine Stemke‐Hale(1), Michael Hauptmann(1), Gordon B. Mills(1), Marc J. van de Vijver(1), Wouter Nijkamp(1)