Pragati Nigam

North Carolina School of Science and Mathematics — United States

Immunology and Microbiology · Life Sciences

13h-index870citations16works0.02yr avg
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Research Topics

Immunotherapy and Immune Responses(6), HIV Research and Treatment(5), Immune Cell Function and Interaction(5), T-cell and B-cell Immunology(4), Herpesvirus Infections and Treatments(4)

Publications16 total

peleke-1: A Suite of Protein Language Models Fine-Tuned for Targeted Antibody Sequence Generation
2025Open Access
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma
Cancer Gene Therapy·2014· 38 citedOpen Access
New therapeutic approaches for malignant glioma: in search of the Rosetta stone
F1000 Medicine Reports·2012· 51 citedOpen Access
Inducible costimulator (ICOS) regulates the immune response in a mouse brain tumor model (127.12)
The Journal of Immunology·2012
Recent developments on immunotherapy for brain cancer
Expert Opinion on Emerging Drugs·2012· 65 cited
Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques
Blood·2011· 99 citedOpen Access
Loss of IL-17–Producing CD8 T Cells during Late Chronic Stage of Pathogenic Simian Immunodeficiency Virus Infection
The Journal of Immunology·2010· 79 citedOpen Access
Preexisting Vaccinia Virus Immunity Decreases SIV-Specific Cellular Immunity but Does Not Diminish Humoral Immunity and Efficacy of a DNA/MVA Vaccine
The Journal of Immunology·2010· 37 citedOpen Access
Expansion of FOXP3+ CD8 T Cells with Suppressive Potential in Colorectal Mucosa Following a Pathogenic Simian Immunodeficiency Virus Infection Correlates with Diminished Antiviral T Cell Response and Viral Control
The Journal of Immunology·2010· 77 citedOpen Access
OA07-03. Influence of preexisting vaccinia immunity on a DNA/MVA SIV vaccine, decreased cellular immunity but enhanced control of a pathogenic SIV challenge
Retrovirology·2009Open Access
Monkeypox-Induced Immunity and Failure of Childhood Smallpox Vaccination To Provide Complete Protection
Clinical and Vaccine Immunology·2007· 170 citedOpen Access
DNA/MVA HIV-1/AIDS vaccine elicits long-lived vaccinia virus-specific immunity and confers protection against a lethal monkeypox challenge
Virology·2007· 58 citedOpen Access
Defective IL-2 Production by HIV-1-Specific CD4 and CD8 T Cells in an Adolescent/Young Adult Cohort
AIDS Research and Human Retroviruses·2006· 17 cited
A Combination DNA and Attenuated Simian Immunodeficiency Virus Vaccine Strategy Provides Enhanced Protection from Simian/Human Immunodeficiency Virus-Induced Disease
Journal of Virology·2005· 21 citedOpen Access
Studies using a viral challenge and CD8 T cell depletions on the roles of cellular and humoral immunity in the control of an SHIV-89.6P challenge in DNA/MVA-vaccinated macaques
Virology·2005· 41 cited
Long-Lived Poxvirus Immunity, Robust CD4 Help, and Better Persistence of CD4 than CD8 T Cells
Journal of Virology·2004· 117 citedOpen Access

Frequent Co-authors

Rama Rao Amara(11), Sunita Sharma(5), Lakshmi Chennareddi(5), Harriet L. Robinson(5), Sunil Kannanganat(4), Vijayakumar Velu(4), Maciej S. Lesniak(4), Suefen Kwa(3), Bart Thaçi(3), Patricia L. Earl(3), Bernard Moss(3), Brenda Auffinger(3), David C. Montefiori(3), Mariam Siddiqui(2), Derek A. Wainwright(2), Harold M. McClure(2), Yu Han(2), Lilin Lai(2), Benton Lawson(2), Pamela A. Kozlowski(2)