Daniel J. Capon

Galaxy Advanced Engineering (United States) — United States

Immunology and Microbiology · Life Sciences

42h-index17.5kcitations70works0.02yr avg
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Research Topics

HIV Research and Treatment(21), Immune Cell Function and Interaction(16), Monoclonal and Polyclonal Antibodies Research(13), Receptor Mechanisms and Signaling(9), T-cell and B-cell Immunology(6)

Publications70 total

Publisher Correction: Anti-CD19/CD20 bispecific antibody with dual Fc domains mediates enhanced effector functions and durable depletion of memory B cells in vivo
Scientific Reports·2025Open Access
Topologically Engineered, Superdimeric α-CD19 x α-CD20 Bispecific Antibodies with Dual Enhanced Fc Domains: New Class of Natural Killer (NK)/Monocyte Engagers for Deep B Cell Depletion in Lupus Nephritis
Journal of the American Society of Nephrology·2025
Anti-CD19/CD20 bispecific antibody with dual Fc domains mediates enhanced effector functions and durable depletion of memory B cells in vivo
Scientific Reports·2025Open Access
SUPERDIMERIC ANTIBODY-LIKE MOLECULE WITH DUAL FC DOMAINS PROVIDES POTENT B CELL DEPLETION WITH MINIMAL CYTOKINE INDUCTION VIA TARGETING OF CD19, CD20 AND FC GAMMA RECEPTORS
The Journal of Rheumatology·2025Open Access
Abstract 2730: Beyond antibodies and CAR-T: Topologically-engineered, super-dimeric antibody-like molecules with dual Fc domains for trispecific, bivalent targeting of CD19, CD20, and Fcgamma receptors
Cancer Research·2024
Topologically engineered antibodies and Fc-fusion proteins: a new class of multifunctional therapeutic candidates for SARS-CoV-2, cancer, and other disease
2022· 1 citedOpen Access
Mouse Antibodies with Activity Against the SARS-CoV-2 D614G and B.1.351 Variants
2021· 2 cited
Multi Epitope-Targeting Immunoprecipitation Using F(ab′) Fragments with High Affinity and Specificity for the Enhanced Detection of a Peptide with Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry
Analytical Chemistry·2013· 8 cited
Flexible antibodies with nonprotein hinges
Proceedings of the Japan Academy Series B·2011· 7 citedOpen Access
A Novel Phenotypic Drug Susceptibility Assay for Human Immunodeficiency Virus Type 1
Antimicrobial Agents and Chemotherapy·2000· 648 citedOpen Access
Production of Antigen‐Specific Human Antibodies from Mice Engineered with Human Heavy and Light Chain YACs<sup>a</sup>
Annals of the New York Academy of Sciences·1995· 24 cited
Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice
Immunity·1994· 827 cited
Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs
Nature Genetics·1994· 351 citedOpen Access
Gene targeting in normal somatic cells: inactivation of the interferon–γ receptor in myoblasts
Nature Genetics·1994· 56 cited
Immunoadhesins
International Reviews of Immunology·1993· 42 cited
CD4 immunoadhesins in anti-HIV therapy: new developments.
PubMed·1992· 15 cited
Characterization of the human factor VIII gene. 1984.
PubMed·1992· 9 cited
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin.
Proceedings of the National Academy of Sciences·1991· 275 citedOpen Access
Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity.
Proceedings of the National Academy of Sciences·1991· 90 citedOpen Access
Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin
Nature·1991· 63 cited
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Frequent Co-authors

Douglas H. Smith(16), Avi Ashkenazi(10), David V. Goeddel(9), J. Ramachandran(8), Timothy J. Gregory(7), John Winslow(7), Scot A. Marsters(7), Jerome E. Groopman(6), Arthur D. Levinson(5), Peter H. Seeburg(5), Laurence A. Lasky(5), Steven M. Chamow(5), Randal A. Byrn(5), William I. Wood(4), Gordon A. Vehar(4), Richard M. Lawn(4), Ernest G. Peralta(4), Aya Jakobovits(4), Avi Ashkenazi(4), Ellson Y. Chen(3)