Ernest G. Peralta

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index5.0kcitations24works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(13), Ion channel regulation and function(12), Protein Kinase Regulation and GTPase Signaling(6), Neuroscience and Neuropharmacology Research(3), Cardiac electrophysiology and arrhythmias(3)

Publications24 total

Phosphorylation and Nuclear Translocation of a Regulator of G Protein Signaling (RGS10)
Journal of Biological Chemistry·2001· 102 citedOpen Access
Inhibition of a Gi-activated Potassium Channel (GIRK1/4) by the Gq-coupled m1 Muscarinic Acetylcholine Receptor
Journal of Biological Chemistry·2001· 64 citedOpen Access
Single Channel Studies of Inward Rectifier Potassium Channel Regulation by Muscarinic Acetylcholine Receptors
The Journal of General Physiology·2000· 7 citedOpen Access
Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter
Molecular and Cellular Biology·2000· 159 citedOpen Access
Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS
Current Biology·1999· 48 citedOpen Access
The Small GTP-Binding Protein RhoA Regulates a Delayed Rectifier Potassium Channel
Cell·1998· 113 citedOpen Access
Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor
Proceedings of the National Academy of Sciences·1998· 102 citedOpen Access
RGS10 is a selective activator of Gαi GTPase activity
Nature·1996· 357 cited
Identification of domains conferring G protein regulation on inward rectifier potassium channels
Cell·1995· 146 citedOpen Access
Coincidence detection at the level of phospholipase C activation mediated by the m4 muscarinic acetylcholine receptor
Current Biology·1995· 26 citedOpen Access
Dual modulation of a potassium channel by the m1 muscarinic and β2-adrenergic receptors
Life Sciences·1995· 8 cited
Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled m1 muscarinic acetylcholine receptor
Cell·1993· 306 cited
Convenient methods for patterning the adhesion of mammalian cells to surfaces using self-assembled monolayers of alkanethiolates on gold
Journal of the American Chemical Society·1993· 248 cited
New mammalian chloride channel identified by expression cloning
Nature·1992· 323 cited
Spiral Calcium Wave Propagation and Annihilation in <i>Xenopus laevis</i> Oocytes
Science·1991· 731 cited
Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptors
Nature·1991· 206 cited
Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell
Cell·1989· 257 cited
Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes
Nature·1988· 666 cited
An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover
Science·1987· 397 cited
Primary Structure and Biochemical Properties of an M <sub>2</sub> Muscarinic Receptor
Science·1987· 510 cited
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Frequent Co-authors

Avi Ashkenazi(4), John Winslow(4), J. Ramachandran(4), Daniel J. Capon(4), Anthony D. Morielli(4), David E. Clapham(3), James D. Lechleiter(2), Steven Girard(2), Gary L. Peterson(2), Michael I. Schimerlik(2), Patrick J. Casey(2), Reed C. Carroll(2), Renate Hellmiss(2), Walt Ream(2), Maya T. Kunkel(2), Teresa G. Cachero(2), Jason S. Felsch(2), Douglas H. Smith(1), Timothy W. Hunt(1), Timothy A. Fields(1)