Sylvie E. Blondelle

Sanford Burnham Prebys Medical Discovery Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index5.9kcitations115works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(57), Antimicrobial Peptides and Activities(34), Biochemical and Structural Characterization(33), Monoclonal and Polyclonal Antibodies Research(31), Click Chemistry and Applications(10)

Publications115 total

Experimental concepts for linking the biological activities of antimicrobial peptides to their molecular modes of action
Biochimica et Biophysica Acta (BBA) - Biomembranes·2020· 39 cited
Issue Information
Biopolymers·2015Open Access
N-acylated Peptides Derived from Human Lactoferricin Perturb Organization of Cardiolipin and Phosphatidylethanolamine in Cell Membranes and Induce Defects in Escherichia coli Cell Division
PLoS ONE·2014· 39 citedOpen Access
Non-Crystalline Systems
2014
Studies on Lactoferricin-derived Escherichia coli Membrane-active Peptides Reveal Differences in the Mechanism of N-Acylated Versus Nonacylated Peptides
Journal of Biological Chemistry·2011· 58 citedOpen Access
Structural Features Governing the Activity of Lactoferricin-Derived Peptides That Act in Synergy with Antibiotics against <i>Pseudomonas aeruginosa In Vitro</i> and <i>In Vivo</i>
Antimicrobial Agents and Chemotherapy·2010· 54 citedOpen Access
Comparative Immunogenicity of Common and Rare HIV Mutant Peptides
2010
Optimization and High-Throughput Screening of Antimicrobial Peptides
Current Pharmaceutical Design·2010· 45 cited
Generation of robust CD8<sup>+</sup> T‐cell responses against subdominant epitopes in conserved regions of HIV‐1 by repertoire mining with mimotopes
European Journal of Immunology·2010· 14 citedOpen Access
Effective Antimicrobial and Anti-Endotoxin Activity of Cationic Peptides Based on Lactoferricin: A Biophysical and Microbiological Study
Anti-Infective Agents in Medicinal Chemistry·2010· 11 cited
N-Acylation of Antimicrobial Peptides Causes Different Mode of Cell Membrane Damage
Biophysical Journal·2010
Short Membrane Active (Lipo)-peptides - Interplay Of Domain Formation, Membrane Curvature Stress And Cellular Leakage
Biophysical Journal·2009Open Access
Natural mutants of HIV CTL epitopes with enhanced immunogenicity as potential vaccine candidates
Advances in experimental medicine and biology·2009
Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides
BMC Microbiology·2008· 50 citedOpen Access
Membrane curvature stress and antibacterial activity of lactoferricin derivatives
Biochemical and Biophysical Research Communications·2008· 39 cited
Immunogenically optimized peptides derived from natural mutants of HIV CTL epitopes and peptide combinatorial libraries
Biopolymers·2008· 6 cited
The Acyl Group as the Central Element of the Structural Organization of Antimicrobial Lipopeptide
Journal of the American Chemical Society·2007· 40 cited
Identification of a d-amino acid decapeptide HIV-1 entry inhibitor
Biochemical and Biophysical Research Communications·2006· 9 cited
Degeneracy and Repertoire of the Human HIV-1 Gag p1777–85 CTL Response
The Journal of Immunology·2006· 27 citedOpen Access
Can machine learning and combinatorial chemistry coexist? An antimicrobial peptide case study
Kluwer Academic Publishers eBooks·2006· 1 cited
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Frequent Co-authors

Richard A. Houghten(28), Enríque Pérez‐Payá(14), Karl Lohner(12), John M. Ostresh(10), Roman Jerala(7), Clemencia Pinilla(6), Colette T. Dooley(6), Jörg Andrä(6), Jon R. Appel(5), Jutta Eichler(5), Ignacio Moriyón(4), Klaus Brandenburg(4), Dagmar Zweytick(4), Guillermo Martínez de Tejada(4), Behrouz Forood(3), Dianne H. Wilson(3), Ema Takahashi(3), Susana Sánchez-Gómez(3), Boštjan Japelj(3), Richard A. Houghten(2)