Birgit Koch

Leipzig University — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index4.1kcitations83works0.02yr avg
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Research Topics

Bacterial Genetics and Biotechnology(10), Glycosylation and Glycoproteins Research(9), Cytomegalovirus and herpesvirus research(9), Enzyme Structure and Function(7), Cassava research and cyanide(7)

Publications82 total

Barrier-Free Microhabitats: Self-Organized Seclusion in Microbial Communities
2025Open Access
Barrier-Free Microhabitats: Self-Organized Seclusion in Microbial Communities
arXiv (Cornell University)·2025Open Access
Expression, Localization, and Protein Interactions of the Partitioning Proteins in the Gonococcal Type IV Secretion System
Frontiers in Microbiology·2021· 7 citedOpen Access
Protein interactions within and between two F‐type type IV secretion systems
Molecular Microbiology·2020· 16 citedOpen Access
Short-Range Order Minerals Inhibit Taxon-Specific Bacterial Growth Rate with and without Fresh Plant Carbon
AGU Fall Meeting Abstracts·2019
HipA-Mediated Phosphorylation of SeqA Does not Affect Replication Initiation in Escherichia coli
Frontiers in Microbiology·2018· 5 citedOpen Access
Macrophage-derived extracellular vesicles mediate a long-lasting innate immune response against hepatitis C virus
Journal of Hepatology·2017
Synthesis and cell-free cloning of DNA libraries using programmable microfluidics
Nucleic Acids Research·2015· 30 citedOpen Access
IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes
Biological Chemistry·2015· 28 cited
Mouse strain and brain region‐specific expression of the glutaminyl cyclases QC and isoQC
International Journal of Developmental Neuroscience·2014· 18 cited
Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease
Journal of Alzheimer s Disease·2014· 106 citedOpen Access
Structure–Activity Relationships of Benzimidazole-Based Glutaminyl Cyclase Inhibitors Featuring a Heteroaryl Scaffold
Journal of Medicinal Chemistry·2013· 64 citedOpen Access
Structure of glutaminyl cyclase from<i>Drosophila melanogaster</i>in space group<i>I</i>4
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2013· 2 citedOpen Access
Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico‐Modeling/Site‐Directed Mutagenesis Approach: Implications for Drug Development
Chemical Biology & Drug Design·2012· 15 citedOpen Access
Crystal Structures of Glutaminyl Cyclases (QCs) from<i>Drosophila melanogaster</i>Reveal Active Site Conservation between Insect and Mammalian QCs
Biochemistry·2012· 14 cited
Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster
2012
Structure of C113A/C136A mutant variant of glycosylated glutaminyl cyclase from Drosophila melanogaster
2012
Structure of glycosylated glutaminyl cyclase from Drosophila melanogaster
2012
rctB mutations that increase copy number of Vibrio cholerae oriCII in Escherichia coli
Plasmid·2012· 17 cited
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Physical Review B·2011· 24 cited
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Frequent Co-authors

Hans‐Ulrich Demuth(12), Stephan Schilling(9), Birger Lindberg Møller(8), Barbara Ann Halkier(7), G. R. F. Krueger(7), Holger Cynis(6), Michael Wermann(6), Ole Nybroe(5), Ole Sibbesen(5), Michael Givskov(4), Steffen Roßner(4), Jens‐Ulrich Rahfeld(4), Mirko Buchholz(4), Alexander Waniek(3), Astrid Kehlen(3), Anett Stephan(3), Torsten Hoffmann(3), Ulrich Heiser(3), Albert Ramon(3), Staffan Kjelleberg(2)