Stephan Schilling

Anhalt University of Applied Sciences — Germany

Medicine · Health Sciences

35h-index4.5kcitations93works0.32yr avg
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Research Topics

Alzheimer's disease research and treatments(39), Amino Acid Enzymes and Metabolism(32), Neuroscience and Neuropharmacology Research(15), Glycosylation and Glycoproteins Research(15), Enzyme Structure and Function(9)

Publications90 total

Omega-3 Source Matters: Comparative Lipid Signatures and Quantitative Distribution of EPA/DHA Across Marine Resources
Marine Drugs·2025Open Access
Investigating the Effects of C1q‐Blocking Using a CDC‐Mutant 3D6 Antibody on ARIA in 5XE4 Mice
Alzheimer s & Dementia·2025Open Access
Sabirnetug shows superior selectivity for Aβ oligomers over monomer compared to recombinant lecanemab and aducanumab
Alzheimer s & Dementia·2025Open Access
Dipeptidyl peptidase 4 deficiency improves survival after focal cerebral ischemia in mice and ameliorates microglia activation and specific inflammatory markers
Neurobiology of Disease·2024· 1 citedOpen Access
„APP family member dimeric complexes are formed predominantly in synaptic compartments“
2022· 1 citedOpen Access
Highly infectious diseases in the Mediterranean Sea area: Inventory of isolation capabilities and recommendations for appropriate isolation
New Microbes and New Infections·2018· 5 citedOpen Access
Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
Journal of Pharmacology and Experimental Therapeutics·2017· 71 citedOpen Access
An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice
Neurobiology of Aging·2015· 51 cited
Phosphate ions and glutaminyl cyclases catalyze the cyclization of glutaminyl residues by facilitating synchronized proton transfers
Bioorganic Chemistry·2015· 13 cited
O1‐10‐02: TOXIC PGLU‐ABETA IS ENHANCED AND GLUTAMINYL CYCLASE (QC) UP‐REGULATED EARLY IN ALZHEIMER'S DISEASE (AD): INHIBITORS OF QC BLOCKING PGLU‐ABETA FORMATION ARE IN CLINICAL DEVELOPMENT
Alzheimer s & Dementia·2014· 1 citedOpen Access
Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease
Journal of Alzheimer s Disease·2014· 106 citedOpen Access
Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death
Neurobiology of Disease·2013· 26 citedOpen Access
Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration
BMC Neuroscience·2013· 32 citedOpen Access
O2–07–02: Characterization of double transgenic mice, APPSLxhQC, exhibiting enhanced pyroGlu3‐beta‐amyloid formation to evaluate efficacy of glutaminyl cyclase (QC) inhibitors
Alzheimer s & Dementia·2013
O1–11–04: PGlu‐beta‐amyloid peptides, highly abundant in Alzheimer's disease brain, are cytotoxic <i>in vitro</i>, <i>in situ</i> and <i>in vivo</i>
Alzheimer s & Dementia·2013
P2–412: Passive immunization against pyroglutamate‐3 beta‐amyloid decreases total plaque load in the absence of microhemorrhage and attenuates cognitive deficits in APP/PS1dE9 mice
Alzheimer s & Dementia·2013
Pyroglutamate-3 Amyloid-β Deposition in the Brains of Humans, Non-Human Primates, Canines, and Alzheimer Disease–Like Transgenic Mouse Models
American Journal Of Pathology·2013· 113 citedOpen Access
Inhibition of Glutaminyl Cyclases alleviates <scp>CCL</scp>2‐mediated inflammation of non‐alcoholic fatty liver disease in mice
International Journal of Experimental Pathology·2013· 34 citedOpen Access
Structure of glutaminyl cyclase from<i>Drosophila melanogaster</i>in space group<i>I</i>4
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2013· 2 citedOpen Access
A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues
Amino Acids·2013· 16 cited
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Frequent Co-authors

Hans‐Ulrich Demuth(39), Holger Cynis(20), Torsten Hoffmann(14), Ulrich Heiser(11), Michael Wermann(10), Sigrid Graubner(7), Steffen Roßner(7), Birgit Koch(7), Jens‐Ulrich Rahfeld(7), Wolfgang Jagla(6), Susanne Manhart(6), Martin Kleinschmidt(6), Astrid Kehlen(5), Alexander Waniek(5), Maike Hartlage‐Rübsamen(5), Claus Wasternack(5), Mirko Buchholz(5), Raik Rönicke(4), Klaus G. Reymann(4), Oliver Wirths(4)