Mark Connors

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

74h-index26.9kcitations192works1.82yr avg
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Research Topics

HIV Research and Treatment(138), Immune Cell Function and Interaction(106), T-cell and B-cell Immunology(58), Cytomegalovirus and herpesvirus research(33), Monoclonal and Polyclonal Antibodies Research(32)

Publications192 total

Incorporation of 5-methylcytidine alleviates RIG-I–mediated innate immune responses to a self-amplifying RNA vaccine
Science Translational Medicine·2025· 1 cited
Intranasal replicating adenovirus type 4-SARS-CoV-2 recombinants induce durable immunity in hamsters 3142
The Journal of Immunology·2025Open Access
Enhanced biophysical characteristics of HIV-specific TCRs in HIV elite controllers drive superior immune control compared to vaccines 3415
The Journal of Immunology·2025Open Access
Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response
Nature Communications·2025Open Access
Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults
The Lancet HIV·2025· 4 cited
Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice
Science Translational Medicine·2025· 4 citedOpen Access
Antigen Dose and Persistence Contribute to Induction of a Durable HIV-1-Specific Neutralizing Antibody Response
2024Open Access
A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies
Cell Reports·2024· 5 citedOpen Access
HIV vaccines induce CD8 <sup>+</sup> T cells with low antigen receptor sensitivity
Science·2023· 16 cited
Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies
UNC Libraries·2023Open Access
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses
UNC Libraries·2023Open Access
Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
Nature Communications·2023· 15 citedOpen Access
Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings
Frontiers in Immunology·2022· 4 citedOpen Access
A trispecific Ab directed to HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
Research Square (Research Square)·2022Open Access
Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings
2022· 2 citedOpen Access
High-Throughput B Cell Epitope Determination by Next-Generation Sequencing
Frontiers in Immunology·2022· 23 citedOpen Access
Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography
Antibodies·2021· 3 citedOpen Access
Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State
mBio·2021· 12 citedOpen Access
Immunologic Control of HIV-1: What Have We Learned and Can We Induce It?
Current HIV/AIDS Reports·2021· 7 cited
Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity <i>Ex Vivo</i> and <i>In Vivo</i>
Journal of Virology·2021· 23 citedOpen Access
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Frequent Co-authors

John R. Mascola(21), Stephen A. Migueles(21), Peter D. Kwong(15), Tongqing Zhou(12), Mark K. Louder(12), Nicole A. Doria‐Rose(12), Krisha McKee(11), Sijy O’Dell(11), Robert T. Bailer(11), Ivelin S. Georgiev(11), Richard A. Koup(9), Baoshan Zhang(9), Xueling Wu(8), Mario Roederer(8), Richard T. Wyatt(8), Claire W. Hallahan(8), Yongping Yang(8), Barton F. Haynes(8), Gwo‐Yu Chuang(8), Stephen D. Schmidt(7)