Rosalie Lawrence

QB3 — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index1.6kcitations33works0.92yr avg
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Research Topics

RNA regulation and disease(15), Viral Infectious Diseases and Gene Expression in Insects(6), RNA Research and Splicing(5), Cellular transport and secretion(5), Heat shock proteins research(5)

Publications33 total

Stereoselective methyl-swapping demonstrates target specificity of cognitive enhancer
2026Open Access
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
Cell·2026· 1 citedOpen Access
eIF2B Selectively Anchors and Activates Mutant KRAS
2025
BPS2025 - A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
Biophysical Journal·2025
BPS2025 - A helical fulcrum in eIF2B coordinates the allosteric regulation of stress signaling
Biophysical Journal·2025
Correction: eIF2B conformation and assembly state regulate the integrated stress response
eLife·2024Open Access
Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins
Molecular Biology of the Cell·2024· 5 citedOpen Access
A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
Nature Chemical Biology·2023· 7 citedOpen Access
A central helical switch controls integrated stress response signaling via eIF2B conformation and assembly
Biophysical Journal·2023Open Access
A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling
2022· 1 citedOpen Access
A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation
eLife·2022· 11 citedOpen Access
Author response: A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation
2022Open Access
Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B
Nature Communications·2021· 20 citedOpen Access
A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation
2021· 1 citedOpen Access
Viral Evasion of the Integrated Stress Response Through Antagonistic eIF2-P Mimicry
2021· 1 citedOpen Access
eIF2B Conformation and Assembly State Regulate the Integrated Stress Response
The FASEB Journal·2021· 4 cited
eIF2B conformation and assembly state regulate the integrated stress response
eLife·2021· 74 citedOpen Access
Author response: eIF2B conformation and assembly state regulate the integrated stress response
2021· 2 citedOpen Access
eIF2B Conformation and Assembly State Regulate the Integrated Stress Response
2020· 4 citedOpen Access
The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form
2020
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Frequent Co-authors

Lan Wang(15), Peter Walter(13), Michael Schoof(12), Morgane Boone(12), Adam Frost(11), Roberto Zoncu(8), James H. Hurley(7), Aniliese Deal(6), Sophie R. Shoemaker(5), Susan Marqusee(5), Dojin Kim(4), Simon A. Fromm(3), Yangxue Fu(3), Peter Walter(3), Lindsey N. Young(2), Avi J. Samelson(2), Ming-Yuan Su(2), Goran Stjepanović(2), J. Zachery Cogan(2), Jennifer Deborah Wuerth(2)