Sean Murphy

Johns Hopkins University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index971citations44works0.42yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Congenital heart defects research(15), Pluripotent Stem Cells Research(11), Tissue Engineering and Regenerative Medicine(6), CRISPR and Genetic Engineering(5), Single-cell and spatial transcriptomics(5)

Publications44 total

Transcriptome-based maturation assessment revealed pro-maturation transcription factors of cardiomyocytes
Frontiers in Bioengineering and Biotechnology·2026Open Access
Machine learning models enhance detection of arrhythmogenic right ventricular cardiomyopathy
Machine Learning Health·2026Open Access
<i>In vivo</i> bioreactor matures iPSC-CMs for MLP disease modeling
2025Open Access
Abstract Fri168: Development of a fluorescence report tagged Titin drug response model in human induced pluripotent stem cells using the TTN intrinsic splicing site.
Circulation Research·2025
Abstract Thu039: <u>Investigating the effects of sympathetic denervation on neonatal cardiac regeneration</u>
Circulation Research·2025
Abstract Thu023: Inter-Organ Comparison Identifies Shared MicroRNAs during Maturation
Circulation Research·2025
Abstract NBT101: m6A mRNA Modifications Regulate Metabolic Transition During Cardiogenesis
Circulation Research·2025
Machine Learning Models Enhance Prediction of Arrhythmogenic Right Ventricular Cardiomyopathy
2025Open Access
A transcriptional enhancer regulates cardiac maturation
Nature Cardiovascular Research·2024· 4 citedOpen Access
Protocol for quantifying stem-cell-derived cardiomyocyte maturity using transcriptomic entropy score
STAR Protocols·2024Open Access
Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells
Nature Communications·2023· 20 citedOpen Access
Cardiac progenitors instruct second heart field fate through Wnts
Proceedings of the National Academy of Sciences·2023· 16 citedOpen Access
Heart-on-a-chip platforms and biosensor integration for disease modeling and phenotypic drug screening
Biosensors and Bioelectronics·2022· 70 cited
Oxysterol misbalance critically contributes to Wilson disease pathogenesis
Science Advances·2022· 13 citedOpen Access
Cross-Organ Transcriptomic Comparison Reveals Universal Factors During Maturation
Journal of Computational Biology·2022· 3 citedOpen Access
Heart neurons use clock genes to control myocyte proliferation
Science Advances·2021· 37 citedOpen Access
Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice
Journal of Clinical Investigation·2021· 40 citedOpen Access
Noncanonical Notch signals have opposing roles during cardiac development
Biochemical and Biophysical Research Communications·2021· 6 citedOpen Access
Noncanonical Notch signals have opposing roles during cardiac development
2021Open Access
Cross-organ transcriptomic comparison reveals universal factors during maturation
2021Open Access
page 1 of 3Next →

Frequent Co-authors

Chulan Kwon(24), Peter Andersen(13), Emmanouil Tampakakis(13), Suraj Kannan(13), Matthew Miyamoto(12), Hideki Uosaki(11), David A. Kass(7), Brian L. Lin(6), Harshi Gangrade(5), Anaïs Kervadec(4), Sandeep Kambhampati(4), Renjun Zhu(4), Alexandre R. Colas(4), Amir Saberi(3), Edrick Sulistio(3), Stephen P. Chelko(3), Brian O’Rourke(3), Myo Htet(3), Elaine Zhelan Chen(3), Xihe Liu(3)