Laurie Jackson‐Grusby

Boston Children's Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index7.4kcitations40works0.02yr avg
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Research Topics

Epigenetics and DNA Methylation(19), Genetic Syndromes and Imprinting(8), Cancer-related gene regulation(8), Pluripotent Stem Cells Research(7), RNA modifications and cancer(7)

Publications40 total

Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells
Stem Cell Reports·2015· 51 citedOpen Access
RUSH and CRUSH: A rapid and conditional RNA interference method in mice
genesis·2013· 2 citedOpen Access
STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation
Journal of Neuroscience·2012· 49 citedOpen Access
The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma
Epigenetics·2012· 52 citedOpen Access
DNA Methylation and the Epigenetic Program in Stem Cells
Humana Press eBooks·2009· 1 cited
Moving AHEAD with an international human epigenome project
Nature·2008· 184 citedOpen Access
“Smad”eningly Erratic: Target Gene Methylation Determines Whether TGFβ Promotes or Suppresses Malignant Glioma
Developmental Cell·2007· 1 citedOpen Access
Suppression of Intestinal Neoplasia by Deletion of <i>Dnmt3b</i>
Molecular and Cellular Biology·2006· 103 citedOpen Access
Global loss of imprinting leads to widespread tumorigenesis in adult mice
Cancer Cell·2006· 9 citedOpen Access
Global loss of imprinting leads to widespread tumorigenesis in adult mice
Cancer Cell·2005· 9 citedOpen Access
Global loss of imprinting leads to widespread tumorigenesis in adult mice
Cancer Cell·2005· 248 cited
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
Proceedings of the National Academy of Sciences·2005· 244 citedOpen Access
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A
Journal of Cell Science·2005· 52 cited
Induction of Tumors in Mice by Genomic Hypomethylation
Science·2003· 1.5k cited
Modeling cancer in mice
Oncogene·2002· 36 cited
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation
Nature Biotechnology·2002· 140 cited
Flp recombinase regulated <i>lacZ</i> expression at the <i>ROSA26</i> locus
genesis·2002· 12 citedOpen Access
Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
Proceedings of the National Academy of Sciences·2001· 615 citedOpen Access
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
Nature Genetics·2001· 695 cited
Generation of mice from wild-type and targeted ES cells by nuclear cloning
Nature Genetics·2000· 344 cited
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Frequent Co-authors

Rudolf Jaenisch(16), Philip Leder(6), William M. Rideout(5), Kevin Eggan(4), Jessica Dausman(3), Caroline Beard(3), Teresa M. Holm(3), Tobias Brambrink(3), Yasuhiro Yamada(3), Daniel I. H. Linzer(3), Thomas Vogt(3), Amir Eden(2), Peter W. Laird(2), Richard Possemato(2), Janet M. Loring(2), Ryuzo Yanagimachi(2), Peter W. Laird(2), Heinz Linhart(2), Haijiang Lin(2), Charles D. Stiles(2)