Sónia Duarte

University of Coimbra — Portugal

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index3.1kcitations26works0.32yr avg
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Research Topics

RNA Interference and Gene Delivery(9), Virus-based gene therapy research(6), Genetic Neurodegenerative Diseases(6), Autophagy in Disease and Therapy(5), RNA Research and Splicing(4)

Publications25 total

rAAV-Delivered Bicistronic Artificial microRNAs for Allele-Specific Silencing Improve Motor and Molecular Outcomes in Spinocerebellar Ataxia Type 3
2025Open Access
A gut miRNA targets cardiolipin synthase and affects mitochondrial function: relevance for Parkinson’s disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024
Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella
Scientific Reports·2024· 1 citedOpen Access
Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects
2024Open Access
Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography
2023· 1 citedOpen Access
Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography
2023· 1 citedOpen Access
miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3
Nucleic Acid Therapeutics·2021· 22 citedOpen Access
Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders
Brain·2019· 72 citedOpen Access
Autophagy activation induced by let-7 microRNA overexpression counteracts disease phenotype in Machado-Joseph disease mouse models
Frontiers in Cellular Neuroscience·2019· 1 citedOpen Access
Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease
Molecular Therapy·2018· 37 citedOpen Access
Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis
Advances in experimental medicine and biology·2018· 22 cited
Let-7 Coordinately Suppresses Components of the Amino Acid Sensing Pathway to Repress mTORC1 and Induce Autophagy
Cell Metabolism·2014· 84 citedOpen Access
DETERMINANTS OF INFANT MORTALITY IN CITIES OF THE JEQUITINHONHA VALLEY, MINAS GERAIS, BRAZIL DETERMINANTES DA MORTALIDADE INFANTIL EM MUNICÍPIOS DO VALE DO JEQUITINHONHA,
2014
Cationic Liposome-Based Systems for Nucleic Acid Delivery: From the Formulation Development to Therapeutic Applications
Advances in predictive, preventive and personalised medicine·2013· 3 cited
Preventive Cancer Stem Cell-Based Vaccination Reduces Liver Metastasis Development in a Rat Colon Carcinoma Syngeneic Model
Stem Cells·2012· 36 citedOpen Access
On the development of antitumoural therapeutic strategies : suicide gene therapy mediated by lipid-based systems and cancer stem-based vaccination
Estudo Geral (Universidad de Coimbra)·2012
Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect
Oncology Reports·2012· 19 citedOpen Access
Suicide gene therapy in cancer: Where do we stand now?
Cancer Letters·2012· 206 cited
Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo
International Journal of Pharmaceutics·2011· 31 cited
Non-covalent association of folate to lipoplexes: A promising strategy to improve gene delivery in the presence of serum
Journal of Controlled Release·2010· 34 cited
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Frequent Co-authors

Luís Pereira de Almeida(10), Maria C. Pedroso de Lima(8), Henrique Faneca(7), Rui Jorge Nobre(7), Diana D Lobo(5), Carina Henriques(5), Magda M. Santana(4), Miguel M. Lopes(4), Georges F. Carle(3), Valérie Pierrefite‐Carle(3), Sara Lopes(3), Dina Pereira(3), Laetitia S. Gaspar(3), Kevin Leandro(3), Ana C. Silva(2), Sara Maria David Trabulo(2), Ana L. Cardoso(2), Catarina Oliveira Miranda(2), João Barata(2), Ana Vasconcelos‐Ferreira(2)