Rui Jorge Nobre

University of Coimbra — Portugal

Neuroscience · Life Sciences

21h-index1.5kcitations57works2.52yr avg
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Research Topics

Genetic Neurodegenerative Diseases(23), Mitochondrial Function and Pathology(13), RNA Interference and Gene Delivery(8), Extracellular vesicles in disease(8), Parkinson's Disease Mechanisms and Treatments(6)

Publications57 total

Exosomes as Emerging Non-Invasive Biomarkers of Cervical Cancer: A Systematic Review and Meta-Analysis
Cancers·2025· 1 citedOpen Access
Extracellular vesicles-associated AAVs for the treatment of Machado-Joseph disease
Molecular Therapy·2025· 1 citedOpen Access
rAAV-Delivered Bicistronic Artificial microRNAs for Allele-Specific Silencing Improve Motor and Molecular Outcomes in Spinocerebellar Ataxia Type 3
2025Open Access
AAV-mediated allele-specific silencing alleviates neuropathology in a novel non-human primate model of Spinocerebellar ataxia type 3
2025Open Access
Differential impact of mutant Ataxin-3 in hindbrain regions: further evidence of white matter loss as a core pathological feature
Experimental Neurology·2025· 1 citedOpen Access
Targeting under-screened women in cervical cancer: combining self-sampling and human papillomavirus testing with a strategic reminder plan
European Journal of Public Health·2025Open Access
Spinocerebellar ataxia type 3: from pathogenesis to promising therapeutics
Trends in Molecular Medicine·2025· 1 cited
Astrocytic mGluR5 signaling tunes emotional and cognitive processing in the adult brain
2025Open Access
Innate immunocompetent iNSpheroids: A hiPSC-derived 3D model to study the central nervous system captures an early CNS response to rAAV
2025Open Access
Gene Editing for <i>ATXN3</i> Inactivation in Machado-Joseph disease: CRISPR-Cas9 as a Therapeutic Alternative to TALEN-Induced Toxicity
2025
A systematic screening assay identifies efficient small guide RNAs for CRISPR activation
Frontiers in Bioengineering and Biotechnology·2025· 1 citedOpen Access
MiR-186-5p inhibition restores synaptic transmission and neuronal network activity in a model of chronic stress
Molecular Psychiatry·2024· 7 citedOpen Access
Exploring the potential of cell-derived vesicles for transient delivery of gene editing payloads
Advanced Drug Delivery Reviews·2024· 19 citedOpen Access
Molecular therapy for polyQ disorders: from bench to clinical trials
Trends in Molecular Medicine·2024· 8 cited
Addressing Cervical Cancer Screening Through Self-Sampling and HPV Testing Among Under-Screened Women: A Case Study in the Decentralized Portuguese Setting
2024Open Access
JoVE Video Dataset
2024Open Access
Viral-based animal models in polyglutamine disorders
Brain·2024· 4 citedOpen Access
RNA-based liposomes for oral cancer: From biophysical characterization to biological evaluation
International Journal of Biological Macromolecules·2024· 7 citedOpen Access
Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects
2024Open Access
Differential Impact of Mutant Ataxin-3 Expression in Different Hindbrain Regions
SSRN Electronic Journal·2024Open Access
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Frequent Co-authors

Luís Pereira de Almeida(42), Diana D Lobo(14), Carina Henriques(14), Miguel M. Lopes(12), Sara Lopes(10), Magda M. Santana(10), David Rufino‐Ramos(7), Sónia Duarte(7), Kevin Leandro(7), Laetitia S. Gaspar(6), João Castelhano(5), José Sereno(5), Miguel Castelo‐Branco(5), Patrícia Albuquerque(4), Cristina Januário(4), Ana C. Silva(4), Catarina Oliveira Miranda(4), Dina Pereira(4), Clévio Nóbrega(4), Ana Carolina da Silva(4)