Clévio Nóbrega

Algarve Biomedical Center — Portugal

Neuroscience · Life Sciences

31h-index5.6kcitations108works8.52yr avg
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Research Topics

Genetic Neurodegenerative Diseases(44), Mitochondrial Function and Pathology(22), CRISPR and Genetic Engineering(13), Autophagy in Disease and Therapy(9), Virus-based gene therapy research(9)

Publications107 total

In Vitro Antiviral Activity of Red Algae Extracts from Chondracanthus teedei var. lusitanicus and Osmundea pinnatifida Against Coxsackievirus A12 and a Lentiviral Vector
Tropical Medicine and Infectious Disease·2026Open Access
Hypothalamic CYP46A1 cholesterol metabolism regulates diet-induced obesity
2026Open Access
Development of a Gene Therapy with Lentiviral Vectors for Spinocerebellar Ataxias
Methods in molecular biology·2025
Molecular hallmarks of neurodegeneration in polyglutamine spinocerebellar ataxias
Cell Death and Disease·2025Open Access
How to find the papers you need to read — and avoid the ones you don’t
Nature·2025
Insights Into Cockayne Syndrome Type B: What Underlies Its Pathogenesis?
Aging Cell·2025· 3 citedOpen Access
Advanced therapy medicinal products development - from guidelines to medicines in the market
Biotechnology Advances·2025· 8 citedOpen Access
Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
GeroScience·2025· 2 citedOpen Access
Gene Editing for <i>ATXN3</i> Inactivation in Machado-Joseph disease: CRISPR-Cas9 as a Therapeutic Alternative to TALEN-Induced Toxicity
2025
Activity induced genes expression is impaired in polyglutamine spinocerebellar ataxias
Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)·2025Open Access
Establishment of an induced pluripotent cell line (ABCRIi001-A) from an elderly female for ageing research
Stem Cell Research·2024Open Access
Making bridges between preclinical and clinical insights into age-related cognitive decline
Neural Regeneration Research·2024Open Access
Oxidative stress and aging: synergies for age related diseases
FEBS Letters·2024· 32 cited
The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease
Cell Death and Disease·2024· 29 citedOpen Access
Brain-targeted drug delivery - nanovesicles directed to specific brain cells by brain-targeting ligands
Journal of Nanobiotechnology·2024· 61 citedOpen Access
The Obese Brain
Obesity·2024· 1 cited
From the disruption of <scp>RNA</scp> metabolism to the targeting of <scp>RNA</scp> ‐binding proteins: The case of polyglutamine spinocerebellar ataxias
Journal of Neurochemistry·2023· 8 citedOpen Access
Assessing cognitive decline in the aging brain: lessons from rodent and human studies
npj Aging·2023· 146 citedOpen Access
Author response for "From the disruption of RNA metabolism to the targeting of RNA-binding proteins: The case of polyglutamine spinocerebellar ataxias"
2023
Reprogramming iPSCs to study age-related diseases: Models, therapeutics, and clinical trials
Mechanisms of Ageing and Development·2023· 12 cited
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Frequent Co-authors

Luís Pereira de Almeida(30), Carlos A. Matos(16), David Albuquerque(12), Liliana Mendonça(11), Adriana Marcelo(8), Licínio Manco(7), Isabel Nascimento-Ferreira(6), Ana Vasconcelos‐Ferreira(6), Sara Carmo‐Silva(6), Rebekah Koppenol(5), David V.C. Brito(5), Hirokazu Hirai(5), Nicole Déglon(5), Cláudia Cavadas(5), Raquel Rodríguez‐López(4), Inês M. Araújo(4), José Bragança(4), Pedro Castelo‐Branco(4), Isabel Onofre(4), Rui Jorge Nobre(4)