Shiroh Futaki

Kyoto University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

71h-index21.1kcitations502works4.72yr avg
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Research Topics

RNA Interference and Gene Delivery(221), Advanced biosensing and bioanalysis techniques(130), Chemical Synthesis and Analysis(96), Lipid Membrane Structure and Behavior(60), Virus-based gene therapy research(59)

Publications502 total

Structural Control of RNA Demethylation: G‐Quadruplex Proximity Suppresses ALKBH5 Activity
Chemistry - A European Journal·2025Open Access
Microcondensate‐Mediated Intracellular Infusion of mRNA Across the Plasma Membrane
Angewandte Chemie·2025
Microcondensate‐Mediated Intracellular Infusion of mRNA Across the Plasma Membrane
Angewandte Chemie International Edition·2025Open Access
A Melittin-Derived Peptide with Improved Cytosolic Delivery Efficiency through Caveolae- and Actin-Mediated Endocytosis
Chemical and Pharmaceutical Bulletin·2025Open Access
e3MPH16: A D-Glutamic Acid-Substituted Peptide for Efficient and Low-Cytotoxicity Cytosolic Delivery of Macromolecules
Chemical and Pharmaceutical Bulletin·2025Open Access
SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein
Biomaterials·2025· 2 citedOpen Access
Membrane Repair Proteins as Negative Regulators of Cytosolic Delivery Using Attenuated Cationic Lytic Peptide L17E and Cell-Penetrating Peptides: Differences and Similarities
Bioconjugate Chemistry·2025
Addition of Oligoarginine to a Membrane Permeabilizing Peptide M-Lycotoxin Facilitates Intracellular Antibody Infusion from Microcondensate
Bioconjugate Chemistry·2025
Physicochemical and cell biological aspects of microcondensate mediated intracellular infusion of antibodies
2025Open Access
Simple Cytosolic and Nuclear Introduction of Boron Compounds Using Cationic Lipids to Enhance Cancer Cell-Killing Activity in Boron Neutron Capture Therapy
Biological and Pharmaceutical Bulletin·2025Open Access
Sars-Cov-2 Inhibition Through Mrna Delivery Using Engineered Extracellular Vesicles Displaying the Spike Protein
SSRN Electronic Journal·2025Open Access
Discovery and characterization of a high-affinity G-quadruplex binding peptide via mRNA display
SSRN Electronic Journal·2025Open Access
KCNN4 as a genomic determinant of cytosolic delivery by the attenuated cationic lytic peptide L17E
Molecular Therapy·2025· 3 cited
Macropinocytosis and the Related Actin-Driven Cellular Uptake Pathways for Extracellular Fine Particles
2025· 1 citedOpen Access
Polysaccharide-Based Coacervate Microgel Bearing Cationic Peptides That Achieve Dynamic Cell-Membrane Structure Alteration and Facile Cytosolic Infusion of IgGs
Bioconjugate Chemistry·2024· 6 cited
Highly sequence-specific, timing-controllable m <sup>6</sup> A demethylation by modulating RNA-binding affinity of m <sup>6</sup> A erasers
Chemical Communications·2024· 4 cited
Polysaccharides modified with attenuated cationic lytic peptides: Formation of microparticles and their use in cytosolic antibody delivery
2024Open Access
Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles
Pharmaceutical Research·2024· 60 citedOpen Access
An approach for the intracellular delivery of IgG via enzymatic ligation with a cell-permeable attenuated cationic amphiphilic lytic peptide
Bioorganic & Medicinal Chemistry·2024· 7 cited
Highly Sequence-specific, Timing-controllable m <sup>6</sup> A Demethylation by Modulating RNA-binding Affinity of m <sup>6</sup> A Erasers
2024Open Access
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Frequent Co-authors

Ikuhiko Nakase(22), Toshihide Takeuchi(19), Hideyoshi Harashima(14), Kentaro Kogure(8), Yukio Sugiura(7), Hidetaka Akita(6), Seigo Tanaka(5), Astrid Gräslund(5), Arwyn T. Jones(5), Ikramy A. Khalil(5), Tomoki Suzuki(4), Kunihiro Ueda(4), Ülo Langel(4), Akiko Tadokoro(4), Tomoka Takatani‐Nakase(4), Naomi Sakai(4), Stefan Matile(4), Fatemeh Madani(3), Miki Niwa(3), Yoshimasa Kawaguchi(3)