Balraj Doray

Washington University in St. Louis — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.1kcitations60works0.52yr avg
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Research Topics

Cellular transport and secretion(24), Lysosomal Storage Disorders Research(14), Calcium signaling and nucleotide metabolism(11), Glycosylation and Glycoproteins Research(10), Lipid Membrane Structure and Behavior(7)

Publications60 total

An unconventional HxD motif orchestrates coatomer-dependent coronavirus morphogenesis
2025Open Access
Reduced heparan sulfate levels in cerebrospinal fluid reflect brain neuron correction in Sanfilippo B mice
Journal of Clinical Investigation·2025· 1 citedOpen Access
GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice
JCI Insight·2025· 1 citedOpen Access
Protocol to measure endogenous GlcNAc-1-phosphotransferase activity in SK-MEL-30 cells
STAR Protocols·2025Open Access
Reduced heparan sulfate levels in cerebrospinal fluid reflect brain neuron correction in Sanfilippo B mice
2025Open Access
Subtle Cellular Phenotypes Inform Pathological and Benign Genetic Mutants in the Iduronidase-2 Sulfatase Gene
2025Open Access
Secretory biogenesis and design of a next-generation coronavirus genetic vaccine
Structural Dynamics·2025Open Access
LYSET facilitates integration of both the N- and C-terminal transmembrane helices/cytoplasmic domains of GlcNAc-1-phosphotransferase
Molecular Biology of the Cell·2025· 1 cited
Molecular Insights into the Regulation of GNPTAB by TMEM251
2024· 1 citedOpen Access
Structure of a truncated human GlcNAc-1-phosphotransferase variant reveals the basis for its hyperactivity
Journal of Biological Chemistry·2024· 2 citedOpen Access
GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice
2024Open Access
Structural restraints in the SARS-CoV-2 spike tail control its intra-cellular trafficking to virion assembly and immune presentation sites
Biophysical Journal·2024
Gene therapy with AAV-S1S3 improves disease in mucolipidosis type II mice
Molecular Genetics and Metabolism·2024
A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs
Nature Communications·2023· 16 citedOpen Access
Structural insights into <i>N</i>-linked glycan remodeling of the SARS-Cov-2 spike protein
Acta Crystallographica Section A Foundations and Advances·2023
Atomic-level determinants of SARS-Cov-2 spike trafficking during infection and vaccination
Acta Crystallographica Section A Foundations and Advances·2023Open Access
A single C-terminal residue controls SARS-CoV-2 spike trafficking and virion assembly
2023· 3 citedOpen Access
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19
Nature Communications·2022· 62 citedOpen Access
Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation
Nature Structural & Molecular Biology·2022· 19 citedOpen Access
Co-expression of S1S3 phosphotransferase in production cell line improves mannose 6-phosphorylation and cellular uptake of alpha--acetylglucosaminidase (Sanfilippo syndrome type B)
Molecular Genetics and Metabolism·2022
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Frequent Co-authors

Stuart Kornfeld(25), Benjamin C. Jennings(13), Lin Liu(7), Debajit Dey(6), Suruchi Singh(6), S. Saif Hasan(6), Byron Kemper(5), Enya Qing(5), Tom Gallagher(5), Steven Q. Le(5), Patricia Dickson(5), Wang‐Sik Lee(4), Whitaker Cohn(4), Lokesh Gakhar(4), Nicholas Schnicker(4), Brian G. Pierce(4), Julian P. Whitelegge(4), John Orban(4), Pradipta Ghosh(3), Tang Suisheng(3)