Valérie Fritsch

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index994citations36works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(32), RNA and protein synthesis mechanisms(17), Advanced biosensing and bioanalysis techniques(12), Chemical Synthesis and Analysis(9), RNA modifications and cancer(4)

Publications36 total

The Endless Subtleties of RNA-Protein Complexes
Structure·2011· 5 citedOpen Access
The Architectural Motifs of Folded RNAs
2010· 3 cited
Molecular Adaptation in RNA Complexes
Structure·2009· 9 citedOpen Access
Introduction to non-watson-crick base pairs and RNA folding. In Multiple aspects of DNA : from Biophysics to Bioinformatics
HAL (Le Centre pour la Communication Scientifique Directe)·2005
Course 2 Introduction to non-watson-crick base pairs and RNA folding
˜Les œHouches/Les Houches·2005
RNA folding: beyond Watson–Crick pairs
Structure·2000· 139 citedOpen Access
Amide-Modified Oligonucleotides with Preorganized Backbone and Furanose Rings: Highly Increased Thermodynamic Stability of the Duplexes Formed with their RNA and DNA Complements
Synlett·1997· 19 cited
Amide backbone modifications for antisense oligonucleotides carrying potential intercalating substituents: Influence on the thermodynamic stability of the corresponding duplexes with RNA- and DNA- complements
Bioorganic & Medicinal Chemistry Letters·1997· 6 cited
Stark erhöhte Affinität modifizierter Oligonucleotide mit in ihrer Konformation eingeschränkten Furanose‐Ringen für komplementäre RNA‐Stränge
Angewandte Chemie·1996· 4 cited
Amide Backbones with Conformationally Restricted Furanose Rings: Highly Improved Affinity of the Modified Oligonucleotides for Their RNA Complements
Angewandte Chemie International Edition in English·1996· 77 cited
The Use of Molecular Dynamics Simulations for Modelling Nucleic Acids
1995· 5 cited
ChemInform Abstract: Synthetic Modifications of Antisense Oligonucleotides: Novel Backbone Replacements with Improved Properties.
ChemInform·1995
Molecular Mechanics and Dynamics Studies on Amide-Modified Backbones in Antisense Oligodeoxynucleotides
ACS symposium series·1995· 1 cited
Molecular mechanics and dynamics studies on two structurally related amide-modified DNA backbones for antisense technology
Bioorganic & Medicinal Chemistry·1995· 17 cited
IMPROVEMENT OF ANTISENSE OLIGONUCLEOTIDES BY SYNTHETIC MODIFICATIONS
European Journal of Medicinal Chemistry·1995· 2 cited
Novel Backbone Replacements for Oligonucleotides
ACS symposium series·1994· 8 cited
Comparison of two amides as backbone replacement of the phosphodiester linkage in oligodeoxynucleotides
Tetrahedron Letters·1994· 51 cited
Molecular Dynamics Simulations of a r(GA<sub>12</sub>G)·d(CT<sub>12</sub>C) Hybrid Duplex
Journal of Biomolecular Structure and Dynamics·1994· 15 cited
ChemInform Abstract: Amides as Substitute for the Phosphodiester Linkage in Antisense Oligonucleotides.
ChemInform·1994
ChemInform Abstract: Ureas as Backbone Replacements for the Phosphodiester Linkage in Oligonucleotides.
ChemInform·1994· 1 cited
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Frequent Co-authors

Romain M. Wolf(21), Alain De Mesmaeker(20), Jacques Lebreton(16), Adrian Waldner(13), Éric Westhof(10), Susan M. Freier(6), E. Westhof(5), A. WALDNER(5), P. Hoffmann(2), Catherine Lesueur(2), Marc‐Olivier Bévièrre(2), Chantal Jouanno(2), Sebastian Wendeborn(2), Karsten Rippe(1), Thomas M. Jovin(1), S. Brahms(1), J. Brahms(1), G. Ravishanker(1), D. L. Beveridge(1), Marcel J. J. Blommers(1)