Adrian Waldner

Novartis (Switzerland) — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index1.5kcitations50works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(20), Advanced biosensing and bioanalysis techniques(11), RNA and protein synthesis mechanisms(10), Chemical Reaction Mechanisms(10), Radical Photochemical Reactions(7)

Publications50 total

Highly Oriented, Self-Assembled Alkanephosphate Monolayers on Tantalum(V) Oxide Surfaces
Langmuir·1999· 106 cited
All-Solid-State Miniaturized Fluorescence Sensor Array for the Determination of Critical Gases and Electrolytes in Blood
Analytical Chemistry·1997· 47 cited
Stark erhöhte Affinität modifizierter Oligonucleotide mit in ihrer Konformation eingeschränkten Furanose‐Ringen für komplementäre RNA‐Stränge
Angewandte Chemie·1996· 4 cited
Amide Backbones with Conformationally Restricted Furanose Rings: Highly Improved Affinity of the Modified Oligonucleotides for Their RNA Complements
Angewandte Chemie International Edition in English·1996· 77 cited
Hydrophobic effects in duplexes with modified oligonucleotide backbones and RNA
Bioorganic & Medicinal Chemistry Letters·1996· 10 cited
Backbone modifications in oligonucleotides and peptide nucleic acid systems
Current Opinion in Structural Biology·1995· 135 cited
Molecular mechanics and dynamics studies on two structurally related amide-modified DNA backbones for antisense technology
Bioorganic & Medicinal Chemistry·1995· 17 cited
Thiocarbamates as Novel Backbone Analogs in Oligonucleotides
Synlett·1995· 10 cited
IMPROVEMENT OF ANTISENSE OLIGONUCLEOTIDES BY SYNTHETIC MODIFICATIONS
European Journal of Medicinal Chemistry·1995· 2 cited
Novel Backbone Replacements for Oligonucleotides
ACS symposium series·1994· 8 cited
Comparison of two amides as backbone replacement of the phosphodiester linkage in oligodeoxynucleotides
Tetrahedron Letters·1994· 51 cited
Comparison of rigid and flexible backbones in antisense oligonucleotides
Bioorganic & Medicinal Chemistry Letters·1994· 19 cited
Amides as a New Type of Backbone Modification in Oligonucleotides
Angewandte Chemie International Edition in English·1994· 119 cited
Synthesis of Oligodeoxyribonucleotides containing dimers with carbamate moieties as replacement of the natural phosphodiester linkage
Bioorganic & Medicinal Chemistry Letters·1994· 17 cited
Amidverbrückung, eine neue Art der Modifizierung von Oligonucleotidrückgraten
Angewandte Chemie·1994· 16 cited
C(5)-Epimerization in Glycopyranosides during the Cyclization of anomeric Radicals: Ease of the intramolecular 1,5-Hydrogen Atom Transfer
Synlett·1994· 21 cited
Ureas as Backbone Replacements for the Phosphodiester Linkage in Oligonucleotides
Synlett·1994· 27 cited
Antisense Oligonucleotides with Alternating Phosphodiester-"Amide-3" Linkages
Synlett·1994· 44 cited
SYNTHETIC MODIFICATIONS OF ANTISENSE OLIGONUCLEOTIDES: NOVEL BACKBONE REPLACEMENTS WITH IMPROVED PROPERTIES
Bulletin des Sociétés Chimiques Belges·1994· 9 cited
Replacement of the phosphodiester linkage in oligonucleotides: Comparison of two structural amide isomers
Bioorganic & Medicinal Chemistry Letters·1994· 28 cited
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Frequent Co-authors

Alain De Mesmaeker(28), Jacques Lebreton(14), Valérie Fritsch(13), Romain M. Wolf(13), C. A. Grob(13), P. Hoffmann(9), Tammo Winkler(7), Susan M. Freier(4), G. VON SPRECHER(4), Catherine Lesueur(3), W. Fischer(3), Reinhard Hanreich(3), Thomas L. Mindt(3), Sebastian Wendeborn(2), Markus Ehrat(2), Ulrich Zutter(2), Marc‐Olivier Bévièrre(2), Daniella Denenmark(2), Paul Hug(2), Bettina Günther(2)