Gonçalo Castelo‐Branco

Karolinska Institutet — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index17.3kcitations125works13.42yr avg
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Research Topics

Single-cell and spatial transcriptomics(41), Neurogenesis and neuroplasticity mechanisms(34), Neuroinflammation and Neurodegeneration Mechanisms(25), RNA Research and Splicing(19), Genomics and Chromatin Dynamics(16)

Publications125 total

Distinct radial glia subtypes regulate midbrain dopaminergic neuron development
Nature Neuroscience·2026Open Access
Neuronal synapses are stabilised by activity-dependent vesicular release from oligodendrocyte precursor cells
2026Open Access
Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells
Figshare·2026Open Access
Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells
Figshare·2026Open Access
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Cell·2026· 2 citedOpen Access
Anoctamin-2-specific T Cells Link Epstein-Barr Virus to Multiple Sclerosis
2025
Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis
Nature Neuroscience·2025Open Access
Oligodendroglia as functional effectors of Multiple Sclerosis risk variants
2025
Spatial dynamics of brain development and neuroinflammation
Nature·2025· 9 citedOpen Access
Cracking glioblastoma core regulatory codes
Nature Cell Biology·2025
Bridging the gap: 150μm resolution whole brain ex-vivo imaging at 7T with RF shimming
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Dual role of GABA <sub>B</sub> receptor in oligodendrocyte function and immune modulation in experimental multiple sclerosis
2025Open Access
Multi-omics Profiling of the Lateral Ventricle Choroid Plexus Reveals Developmental Cellular Remodeling, Early Immune Gene Activation, and a Novel Epithelial Subtype
2025Open Access
Heparan sulfate Sulfatases are essential for patterning of human stem cell-derived midbrain dopaminergic neurons
2025Open Access
Multi-omics reveal critical differentiation target for Parkinson’s Disease-vulnerable midbrain dopaminergic neurons
2025Open Access
G-quadruplex profiling in complex tissues using single-cell CUT&amp;Tag
2025· 2 citedOpen Access
Quantitative characterization of cell niches in spatially resolved omics data
Nature Genetics·2025· 35 citedOpen Access
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses
Universität Zürich, ZORA·2025Open Access
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses
Neuron·2024· 36 citedOpen Access
Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Nature Neuroscience·2024· 1 citedOpen Access
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Frequent Co-authors

Ernest Arenas(12), Eneritz Agirre(12), David van Bruggen(10), Ana Mendanha Falcão(9), Petra Kukanja(9), Kyle M. Sousa(7), Sten Linnarsson(6), Sueli Marques(6), Mandy Meijer(6), Marek Bartošovič(6), Gioele La Manno(5), Patrik Ernfors(5), Sarah Jäkel(5), Anna Williams(5), Nina Rawal(5), Leslie A. Kirby(5), Amit Zeisel(4), Peter Lönnerberg(4), Erik Sundström(4), Jens Hjerling‐Leffler(4)