Nanna S. Mikkelsen

Aarhus University — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index326citations17works9.12yr avg
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Research Topics

CRISPR and Genetic Engineering(9), Virus-based gene therapy research(5), CAR-T cell therapy research(3), RNA regulation and disease(3), Acute Myeloid Leukemia Research(2)

Publications16 total

Cholesterol Biosynthesis is a Targetable Vulnerability of <i>CEBPA</i> -mutant Acute Myeloid Leukemia
2026Open Access
Orthogonal CRISPR systems for targeted integration and multiplex base editing enable nonviral engineering of allogeneic CAR-T cells
Molecular Therapy·2025· 4 citedOpen Access
Single-stranded HDR templates with truncated Cas12a-binding sequences improve knock-in efficiencies in primary human T cells
Molecular Therapy — Nucleic Acids·2025· 5 citedOpen Access
Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells
2024
3027 – TET2 AND WT1 MUTATIONS ACCELERATE CEBPA P30 LEUKEMIA DEVELOPMENT
Experimental Hematology·2024
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer
Communications Biology·2024· 33 citedOpen Access
CRISPR activation to characterize splice-altering variants in easily accessible cells
The American Journal of Human Genetics·2024· 18 citedOpen Access
Novel BAFF-R-specific chimeric antigen receptor T cell therapy controls but do not eradicate mantle-cell lymphoma in a preclinical mouse model
University of Southern Denmark Research Portal (University of Southern Denmark)·2024Open Access
Enrichment strategies to enhance genome editing
Journal of Biomedical Science·2023· 25 citedOpen Access
Enrichment of transgene integrations by transient CRISPR activation of a silent reporter gene
Molecular Therapy — Methods & Clinical Development·2023· 8 citedOpen Access
A truncated reverse transcriptase enhances prime editing by split AAV vectors
Molecular Therapy·2022· 91 citedOpen Access
3065 – CRISPR MODELING OF ACUTE MYELOID LEUKEMIA MUTATIONS IN PRIMARY HEMATOPOIETIC STEM CELLS TO STUDY (PRE-)LEUKEMIA DEVELOPMENT
Experimental Hematology·2022
A truncated reverse transcriptase enhances prime editing by split AAV vectors
2021· 10 citedOpen Access
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi
Genome Research·2021· 80 citedOpen Access
Recovery period of Folsomia candida influence the impact of nonylphenol and phenanthrene on the tolerance of drought and heat shock
Environmental Pollution·2019· 10 cited
Recombinant Uracil Phosphoribosyltransferase from the ThermophileBacillus caldolyticus:Expression, Purification, and Partial Characterization
Protein Expression and Purification·1997· 20 cited

Frequent Co-authors

Rasmus O. Bak(14), Zongliang Gao(3), Sujan Ravendran(3), Bauke de Boer(3), Mikkel Bruhn Schuster(3), Erwin M. Schoof(3), Kim Theilgaard‐Mönch(3), Bo Porse(3), Jakob Haldrup(2), Martin K. Thomsen(2), Jacob Giehm Mikkelsen(2), Trine I. Jensen(2), Thorkild Terkelsen(2), Ana-Maria Nitulescu(2), Weijie Du(2), Viktor Glaser(2), Jonas Kath(2), Robert Greensmith(2), Maik Stein(2), Michael M. Kaminski(2)