Ned Van Eps

Thermo Fisher Scientific (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index3.7kcitations56works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(38), Photoreceptor and optogenetics research(30), Electron Spin Resonance Studies(13), Nitric Oxide and Endothelin Effects(11), Photosynthetic Processes and Mechanisms(7)

Publications56 total

Kinetic characterization of sera antibodies – A surface plasmon resonance study
Human Immunology·2024
Mapping the conformational landscape of the stimulatory heterotrimeric G protein
Nature Structural & Molecular Biology·2023· 27 cited
Site‐directed mutagenesis of <scp>HLA</scp> molecules reveals the functional epitope of a human <scp>HLA‐A1</scp>/<scp>A36</scp>‐specific monoclonal antibody
HLA·2022· 7 citedOpen Access
Mapping the conformational landscape of the stimulatory heterotrimeric G protein
2022· 1 citedOpen Access
Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents
Journal of the American Chemical Society·2020· 48 citedOpen Access
Cryo-EM structure of the native rhodopsin dimer in nanodiscs
Journal of Biological Chemistry·2019· 82 citedOpen Access
X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin
Scientific Reports·2019· 68 citedOpen Access
Divergent conformations of the arrestin-rhodopsin complex in solution
Investigative Ophthalmology & Visual Science·2019Open Access
A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin
Journal of Molecular Biology·2018· 14 cited
Conformational flexibility of the arrestin-rhodopsin complex.
Investigative Ophthalmology & Visual Science·2018Open Access
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
Nature·2018· 4 citedOpen Access
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
Nature·2018· 273 citedOpen Access
Rhodopsin-Gi complex
2018
G<sub>i</sub>- and G<sub>s</sub>-coupled GPCRs show different modes of G-protein binding
Proceedings of the National Academy of Sciences·2018· 75 citedOpen Access
Structure of the glucagon receptor in complex with a glucagon analogue
Nature·2018· 139 cited
Utilizing tagged paramagnetic shift reagents to monitor protein dynamics by NMR
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2017· 4 cited
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors
Cell·2017· 439 citedOpen Access
Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser
2017
Conformational equilibria of light-activated rhodopsin in nanodiscs
Proceedings of the National Academy of Sciences·2017· 95 citedOpen Access
Exploring Complexes of Rhodopsin and Binding Partners in Virtual Reality
Biophysical Journal·2017Open Access
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Frequent Co-authors

Wayne L. Hubbell(30), Oliver P. Ernst(20), Vsevolod V. Gurevich(16), Sergey A. Vishnivetskiy(11), Susan M. Hanson(10), Takefumi Morizumi(9), Derek J. Francis(8), Candice S. Klug(8), H. Eric Xu(7), Parker W. de Waal(6), Karsten Melcher(6), Heidi E. Hamm(6), Ng Lydia(5), Yanyong Kang(4), Xin Gu(4), Patrick R. Griffin(4), Raymond C. Stevens(4), Yanting Yin(4), R. Scott Prosser(4), William M. Oldham(4)