Neil R. Norcross

University of Dundee — United Kingdom

Medicine · Health Sciences

15h-index1.3kcitations36works3.82yr avg
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Research Topics

Trypanosoma species research and implications(7), Crystallization and Solubility Studies(6), X-ray Diffraction in Crystallography(6), Malaria Research and Control(5), Research on Leishmaniasis Studies(5)

Publications36 total

Compounds Reducing Human Sperm Motility as Potential Nonhormonal Contraceptives Identified Using a High-Throughput Phenotypic Screening Platform
ACS Omega·2025Open Access
Compounds reducing human sperm motility as potential non hormonal contraceptives identified using a high-throughput phenotypic screening platform
2025Open Access
<i>Cryptosporidium</i> lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
Science Translational Medicine·2024· 12 citedOpen Access
Sperm Toolbox—A selection of small molecules to study human spermatozoa
PLoS ONE·2024· 3 citedOpen Access
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Journal of Medicinal Chemistry·2023· 18 citedOpen Access
Sperm Toolbox – A selection of small molecules to study human spermatozoa
2023· 1 citedOpen Access
Male contraceptive development: A medicinal chemistry perspective
European Journal of Medicinal Chemistry·2022· 9 citedOpen Access
Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform
Human Reproduction·2022· 11 citedOpen Access
Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform
2021· 2 citedOpen Access
Substituted Aminoacetamides as Novel Leads for Malaria Treatment
ChemMedChem·2019· 7 citedOpen Access
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
Proceedings of the National Academy of Sciences·2019· 132 citedOpen Access
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and a difluoro cyclohexyl chromone ligand
2018
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
Journal of Medicinal Chemistry·2016· 89 citedOpen Access
Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials
Journal of Medicinal Chemistry·2016· 18 citedOpen Access
Erratum: Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis
Nature·2016· 6 citedOpen Access
Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi
PLoS neglected tropical diseases·2016· 27 citedOpen Access
Discovery of Inhibitors of <i>Trypanosoma brucei</i> by Phenotypic Screening of a Focused Protein Kinase Library
ChemMedChem·2015· 17 citedOpen Access
A novel multiple-stage antimalarial agent that inhibits protein synthesis
Nature·2015· 452 citedOpen Access
Lead Optimization of a Pyrazole Sulfonamide Series of <i>Trypanosoma brucei</i> <i>N</i> -Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis
Journal of Medicinal Chemistry·2014· 72 citedOpen Access
Substituted 2-Phenylimidazopyridines: A New Class of Drug Leads for Human African Trypanosomiasis
Journal of Medicinal Chemistry·2013· 74 citedOpen Access
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Frequent Co-authors

Ian H. Gilbert(22), Kevin D. Read(18), Irene Hallyburton(10), Paul G. Wyatt(10), Caroline Wilson(10), Peter C. Astles(10), Paul R. Blakemore(10), Beatriz Baragaña(9), Suzanne Norval(9), Laste Stojanovski(9), Julie A. Frearson(9), Stuart L. Warriner(9), Alan H. Fairlamb(8), C.A. Kilner(8), Jennifer Riley(7), David W. Gray(7), J.P. Melbardis(7), M.F. Solera(7), Mark A. Sephton(7), Franz Gruber(7)