Paul G. Wyatt

University of Dundee — United Kingdom

Medicine · Health Sciences

48h-index8.9kcitations197works0.72yr avg
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Research Topics

Trypanosoma species research and implications(48), Research on Leishmaniasis Studies(43), Tuberculosis Research and Epidemiology(21), Synthesis and Biological Evaluation(21), Biochemical and Molecular Research(20)

Publications197 total

Nanomolar Acoustic Droplet Ejection to Measure Plate Based Chemistry Reactivity Profiles
2025
Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis
Journal of Medicinal Chemistry·2025Open Access
Design and development of lysyl tRNA synthetase inhibitors, for the treatment of tuberculosis
2025· 1 citedOpen Access
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>
ACS Infectious Diseases·2025· 2 citedOpen Access
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
PLoS ONE·2024Open Access
Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV‐CA Binding Fragments
ChemMedChem·2024· 1 citedOpen Access
Design of the Global Health chemical diversity library v2 for screening against infectious diseases
PLoS neglected tropical diseases·2023· 4 citedOpen Access
Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments
2023Open Access
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Journal of Medicinal Chemistry·2023· 18 citedOpen Access
Encouraging Student Attendance and Engagement in Lectures &amp; Workshops in the Pre- and Post-Covid World
CHIMIA International Journal for Chemistry·2023· 2 citedOpen Access
Correction to “Bespoke Drug Discovery Training for Low-Middle Income Countries”
ACS Medicinal Chemistry Letters·2023Open Access
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
Nature·2023Open Access
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static–Cidal Screening of Analogues
Journal of Medicinal Chemistry·2023· 6 citedOpen Access
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
Nature Communications·2022· 29 citedOpen Access
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity
Structure·2022· 42 citedOpen Access
Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease
European Journal of Medicinal Chemistry·2022· 10 citedOpen Access
CCDC 2034666: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity
2022· 6 citedOpen Access
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
Journal of Medicinal Chemistry·2021· 33 citedOpen Access
Ligand binding: evaluating the contribution of the water molecules network using the Fragment Molecular Orbital method
Journal of Computer-Aided Molecular Design·2021· 14 citedOpen Access
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Frequent Co-authors

Ian H. Gilbert(24), Alan H. Fairlamb(18), Julie A. Frearson(17), Kevin D. Read(17), Laste Stojanovski(12), David W. Gray(10), Leah S. Torrie(10), Irene Hallyburton(9), Michael A. J. Ferguson(9), Ruth Brenk(8), Fabio Zuccotto(8), Frederick R. C. Simeons(8), Laura A. T. Cleghorn(8), Neil R. Norcross(7), Maria Osuna‐Cabello(7), Jennifer Riley(7), Stephen Brand(7), Suzanne Norval(6), Manu De Rycker(6), Susan Wyllie(6)