Aohua Deng

Northwestern Polytechnical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index225citations8works21.22yr avg
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Research Topics

Ubiquitin and proteasome pathways(3), Ferroptosis and cancer prognosis(3), RNA modifications and cancer(3), interferon and immune responses(2), Protein Degradation and Inhibitors(2)

Publications8 total

Innovative PDK1‐Degrading PROTACs Transform Cancer Aerobic Glycolysis and Induce Immunogenic Cell Death in Breast Cancer
Exploration·2025· 10 citedOpen Access
A STING agonist prodrug reprograms tumor-associated macrophage to boost colorectal cancer immunotherapy
Theranostics·2024· 24 citedOpen Access
Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy
Chemical Engineering Journal·2024· 14 cited
A platinum(IV)–artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy
MedComm·2024· 19 citedOpen Access
A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression
Pharmacological Research·2024· 39 citedOpen Access
Novel Pt(IV) complex OAP2 induces STING activation and pyroptosis via mitochondrial membrane remodeling for synergistic chemo-immunotherapy
Acta Pharmaceutica Sinica B·2023· 42 citedOpen Access
Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy
Journal of Medicinal Chemistry·2023· 48 cited
<b>CJ</b><sub><b>2</b></sub>: A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane
Journal of Medicinal Chemistry·2023· 29 cited

Frequent Co-authors

Renming Fan(8), Gaofei Wei(8), Ruizhuo Lin(7), Yongrui Hai(7), Junyan Zhuang(6), Ruoxi Sang(3), Jiakui Gou(3), Yang Liu(3), Maosheng Cheng(3), Ting Zhao(3), Ming Zhao(3), Bing Qi(2), Shuo Zhang(2), Le Yang(2), Ting C. Zhao(1), Junke Song(1), Guanhua Du(1), Shan‐Shui Meng(1), Zhuang Hou(1), Lanxin Luo(1)