Aaron McKenna

Dartmouth College — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

43h-index76.6kcitations167works1.52yr avg
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Research Topics

Melanoma and MAPK Pathways(34), Cancer Genomics and Diagnostics(33), Single-cell and spatial transcriptomics(18), Brain Metastases and Treatment(18), Sarcoma Diagnosis and Treatment(17)

Publications164 total

SCOUT: Ornstein–Uhlenbeck modelling of gene expression evolution on single-cell lineage trees
2025Open Access
Mapping Single-Cell ecDNA Dynamics in Glioblastoma with CRISPR Lineage Tracing
International Journal of Radiation Oncology*Biology*Physics·2025
Generations in Flux: Tracking the Birth of Cellular Heterogeneity in Cancer
Cancer Research·2025· 1 cited
BASELINE: A CRISPR Base Editing Platform for Mammalian-Scale Single-Cell Lineage Tracing
2025· 3 citedOpen Access
Hierarchical Lineage Tracing Reveals Diverse Pathways of AML Treatment Resistance
2025· 2 citedOpen Access
The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
Immunity·2025· 7 cited
Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis
2024· 2 citedOpen Access
3009 – APELIN-MEDIATED CLONAL EXPANSION OF NICHE ENDOTHELIAL CELLS DRIVES SELECTION OF LEUKEMIC AND NORMAL HSC CLONES
Experimental Hematology·2024
MSR102 Targeted Immunomodulators for the Treatment of Moderate-to-Severe Plaque Psoriasis: A Network Meta-Analysis Comparing Binomial and Multinomial Approaches
Value in Health·2024Open Access
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection
2024· 1 citedOpen Access
Abstract A028: Subclonal lineage recording in glioblastoma using CRISPR base editing
Cancer Research·2024
Genome Report: chromosome-scale genome assembly of the African spiny mouse (<i>Acomys cahirinus</i>)
G3 Genes Genomes Genetics·2023· 6 citedOpen Access
Abstract A27: Cellular barcoding of the leukemic niche reveals an apelin-mediated clonal expansion of niche endothelial and mesenchymal stromal cell clones
Blood Cancer Discovery·2023· 1 cited
Dynamic single cell lineage recording of endogenous viral specific CD8 T cells reveals multiple potential cell fate pathways
The Journal of Immunology·2023Open Access
GENOME REPORT: Chromosome-scale genome assembly of the African spiny mouse ( <i>Acomys cahirinus</i> )
2023· 4 citedOpen Access
Supplementary File 1 from Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
2023Open Access
Supplementary Table S5 from The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma
2023Open Access
Supplementary Table S16 from The Genomic Landscape of Pediatric Ewing Sarcoma
2023Open Access
Data Supplement from MAP Kinase Pathway Alterations in &lt;i&gt;BRAF&lt;/i&gt;-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition
2023Open Access
Supplementary Table 1 from MAP Kinase Pathway Alterations in &lt;i&gt;BRAF&lt;/i&gt;-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition
2023Open Access
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Frequent Co-authors

Gad Getz(28), Kristian Cibulskis(23), Scott L. Carter(23), Stacey Gabriel(19), Michael S. Lawrence(17), Matthew Meyerson(15), Andrey Sivachenko(13), Carrie Sougnez(13), Levi A. Garraway(11), Petar Stojanov(10), Chip Stewart(10), Daniel Auclair(9), Eliezer M. Van Allen(9), Mara Rosenberg(9), Jay Shendure(9), Eric S. Lander(8), Amaro Taylor‐Weiner(8), Adam Kieżun(7), Erica Shefler(7), Todd R. Golub(7)