Bernard Fermini

Medicine · Health Sciences

35h-index5.1kcitations80works0.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(57), Ion channel regulation and function(42), Neuroscience and Neural Engineering(20), Receptor Mechanisms and Signaling(9), Cardiac Arrhythmias and Treatments(9)

Publications80 total

On the perspective of an aging population and its potential impact on drug attrition and pre-clinical cardiovascular safety assessment
Journal of Pharmacological and Toxicological Methods·2022· 17 citedOpen Access
Comparison between collagen and fibrin matrices in 3D cardiac tissue engineering
Journal of Pharmacological and Toxicological Methods·2021
Use of automated patch clamp in cardiac safety assessment: Past, present & future perspectives
Journal of Pharmacological and Toxicological Methods·2021· 9 citedOpen Access
Use of automated patch clamp in cardiac safety assessment: past, present and future perspectives
Journal of Pharmacological and Toxicological Methods·2021· 36 citedOpen Access
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
Scientific Reports·2020· 3 citedOpen Access
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
Scientific Reports·2020· 59 citedOpen Access
Modeling the Heart With Novoheart’s Myheart™ Platform
Future Drug Discovery·2020Open Access
Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation
Journal of Pharmacological and Toxicological Methods·2019· 1 cited
Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes
Journal of Pharmacological and Toxicological Methods·2019
Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology
Scientific Reports·2019· 94 citedOpen Access
Human Cardiac Ventricular‐Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two‐Tiered Assay for Inotropic Responses
Clinical Pharmacology & Therapeutics·2019· 54 cited
Challenges in designing and executing clinical trials in a dish studies
Journal of Pharmacological and Toxicological Methods·2018· 17 citedOpen Access
Leveraging genetic diversity in vitro: Evolution or revolution in cardiac safety assessment?
Journal of Pharmacological and Toxicological Methods·2018· 1 cited
Clinical Trials in a Dish: A Perspective on the Coming Revolution in Drug Development
SLAS DISCOVERY·2018· 58 citedOpen Access
A SPS Survey on Cardiovascular Safety Pharmacology Practices Assessing Proarrhythmia Risk in Drug Safety Testing: State of the Art Prior to Implementation of the Comprehensive In Vitro Proarrhythmia Assay (CiPA) Paradigm
Journal of Pharmacological and Toxicological Methods·2017
Successes and Challenges of Performing hERG Studies for CiPA
Journal of Pharmacological and Toxicological Methods·2017· 1 cited
Cardiac sodium channel antagonism – Translation of preclinical in vitro assays to clinical QRS prolongation
Journal of Pharmacological and Toxicological Methods·2017· 10 cited
The Evolving Roles of Human iPSC-Derived Cardiomyocytes in Drug Safety and Discovery
Cell stem cell·2017· 74 citedOpen Access
Cardiac voltage-gated ion channels in safety pharmacology: Review of the landscape leading to the CiPA initiative
Journal of Pharmacological and Toxicological Methods·2017· 68 citedOpen Access
Proarrhythmia liability assessment and the comprehensive in vitro Proarrhythmia Assay (CiPA): An industry survey on current practice
Journal of Pharmacological and Toxicological Methods·2017· 34 citedOpen Access
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Frequent Co-authors

Stanley Nattel(20), Zhiguo Wang(11), Gary A. Gintant(4), Joseph J. Salata(4), Anthony A. Fossa(3), David G. Strauss(3), Jules C. Hancox(3), Najah Abi‐Gerges(3), Khuram W. Chaudhary(3), John Koerner(3), Jamie I. Vandenberg(3), Nancy K. Jurkiewicz(3), Dayue Darrel Duan(3), Todd Wisialowski(3), Jianlin Feng(3), Thomas Colatsky(2), Jennifer Pierson(2), Norman Stockbridge(2), Barbara A. Wible(2), Matthew Bridgland‐Taylor(2)