Sai Mukund Ramakrishnan

Washington University in St. Louis — United States

Medicine · Health Sciences

13h-index972citations66works0.92yr avg
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Research Topics

Acute Myeloid Leukemia Research(41), Epigenetics and DNA Methylation(9), Cancer Genomics and Diagnostics(9), Protein Degradation and Inhibitors(9), Immune cells in cancer(4)

Publications66 total

Mechanisms of chemotherapy resistance driven by Mecom overexpression
Blood·2025Open Access
The recurrent AML-associated CBFBD87GDSY mutation has hypomorphic function and is mechanistically distinct from CBFB:MYH11
Blood·2025Open Access
Heterogeneity of immune escape mechanisms in de novo Acute Myeloid Leukemia
Blood·2025Open Access
Overexpression of the signaling coordinator GAB2 can play an important role in acute myeloid leukemia progression
Journal of Clinical Investigation·2025· 2 citedOpen Access
Reduced <i>CBFB</i> Expression Causes Compensatory Upregulation of <i>RUNX1</i> Expression, Defining a Feedback Loop That May be Relevant for AML Pathogenesis
Blood·2024Open Access
VISTA As a Mediator of Immune Suppression in AML Initiated By <i>DNMT3A</i> and <i>NPM1</i> mutations
Blood·2024
Recurrent Amplification of Chromosome 7 in Murine AML with <i>Dnmt3a</i>R878H and <i>Npm1</i>cA Mutations Identifies <i>Gab2</i> As a Possible Therapeutic Target in AML
Blood·2024Open Access
Generation of white light on Dy3+-ions activated Zinc fluoroborate glasses and luminescence studies
Journal of Optics·2024· 2 cited
PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells
Proceedings of the National Academy of Sciences·2024· 4 citedOpen Access
Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes
Haematologica·2024· 2 citedOpen Access
Abstract 5589: <i>CBFB::MYH11</i> expression activates <i>Trp53</i> in myeloid cells, which inhibits cell growth and sensitizes cells to cytarabine
Cancer Research·2024
Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia–initiating CBFB::MYH11 oncofusion protein
Journal of Clinical Investigation·2023· 10 citedOpen Access
Mechanisms of PML::Rara and GATA2 Protein Interactions in Hematopoietic Cells
Blood·2023Open Access
Overexpression of the Signaling Integrator <i>Gab2</i> Accelerates AML Development in Mice with <i>Dnmt3a R878H</i>and <i>Npm1 cA</i> Mutations
Blood·2023Open Access
Genomic landscape of <i>TP53</i>-mutated myeloid malignancies
Blood Advances·2023· 26 citedOpen Access
Supplementary Table from Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia
2023Open Access
Supplementary Table from Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia
2023Open Access
Supplementary Data from Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia
2023Open Access
Supplementary Data from Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia
2023Open Access
Supplementary Table from Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia
2023Open Access
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Frequent Co-authors

Christopher A. Miller(38), Timothy J. Ley(36), Nichole Helton(28), Daniel C. Link(20), John F. DiPersio(18), Sharon E. Heath(18), Jacqueline E. Payton(17), Matthew J. Walter(17), Catrina C. Fronick(16), Robert S. Fulton(16), Sridhar Nonavinkere Srivatsan(16), Peter Westervelt(15), Allegra A. Petti(13), Ryan B. Day(11), Ziheng Xu(11), Saad Khan(10), David H. Spencer(9), Casey Katerndahl(7), Haley Abel(6), David Y. Chen(6)