Luca Biasco

Institute of Infection and Immunity — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index5.6kcitations69works3.22yr avg
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Research Topics

Virus-based gene therapy research(31), CAR-T cell therapy research(27), CRISPR and Genetic Engineering(25), RNA Interference and Gene Delivery(9), Single-cell and spatial transcriptomics(7)

Publications69 total

In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles
Nature Biotechnology·2025· 4 cited
Hierarchical clustering uncovered disease patterns and further untangled complexities in immune complex-mediated idiopathic MPGN and C3 glomerulopathy
Kidney International·2025· 3 citedOpen Access
Mortality and Neurodevelopmental Outcome in an Italian Cohort of Very Low Birth Weight Infants
Acta Paediatrica·2025· 1 citedOpen Access
O-092 - [18F] FDG PET/MR VERSUS STANDARD MRI IN PREDICTING RESPONSE TO NEOADJUVANT TREATMENT IN RECTAL CANCER
Cirugía Española·2024
Preclinical lentiviral hematopoietic stem cell gene therapy corrects Pompe disease-related muscle and neurological manifestations
Molecular Therapy·2024· 5 citedOpen Access
Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article
Human Gene Therapy·2024· 6 citedOpen Access
Preclinical lentiviral vector-mediated hematopoietic stem and progenitor cell gene therapy corrects Pompe disease-related muscle and neurological manifestations
2023Open Access
Efficient and Specific <i>In Vivo</i> Genetic Engineering of Human Hematopoietic Stem Progenitor Cells without Selective Conditioning
Blood·2023Open Access
Tracking hematopoietic stem cell evolution in a Wiskott–Aldrich clinical trial
The Annals of Applied Statistics·2023· 5 cited
Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy
Cancer Cell·2023· 64 citedOpen Access
IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods
BMC Bioinformatics·2023· 5 citedOpen Access
Abstract 4157: Tumor context dictates reliance on TCF1 for response to immunotherapy
Cancer Research·2023
IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods
2023Open Access
Additional file 3 of IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods
Figshare·2023Open Access
Abstract B35: Tumor context dictates reliance on TCF1 for response to immunotherapy
Cancer Immunology Research·2022
TRACKING HEMATOPOIETIC STEM CELL EVOLUTION IN A WISKOTT-ALDRICH CLINICAL TRIAL
2022Open Access
High-throughput analysis of hematopoietic stem cell engraftment after intravenous and intracerebroventricular dosing
Molecular Therapy·2022· 13 citedOpen Access
High-resolution cellular and molecular follow up of lysosomal disease patients treated with hematopoietic stem cell lentiviral gene therapy
Molecular Genetics and Metabolism·2022
Genetically engineered microglia-like cells have therapeutic potential for neurodegenerative disease
2021· 2 citedOpen Access
Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients
Nature Cancer·2021· 132 citedOpen Access
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Frequent Co-authors

Alessandro Aiuti(21), Cristina Baricordi(15), Danilo Pellin(12), Maria Grazia Roncarolo(11), Francesca Dionisio(11), Clelia Di Serio(10), Manfred Schmidt(9), Christof von Kalle(9), Claudio Bordignon(9), Fabio Ciceri(9), Luigi Naldini(9), Serena Scala(9), Alessandra Biffi(8), Eugenio Montini(7), Samantha Scaramuzza(7), Stefania Giannelli(7), Mariana Loperfido(7), Maria Pia Cicalese(6), Francesca Ferrua(5), Adrian J. Thrasher(5)