Chad D. Williamson

Eunice Kennedy Shriver National Institute of Child Health and Human Development — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index1.9kcitations42works1.42yr avg
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Research Topics

Cellular transport and secretion(20), Lysosomal Storage Disorders Research(8), Cytomegalovirus and herpesvirus research(8), Mitochondrial Function and Pathology(7), Calcium signaling and nucleotide metabolism(7)

Publications42 total

Meet the authors: Raffaella De Pace, Chad Williamson, and Juan Bonifacino
Cell chemical biology·2025
BLOC-1 and BORC: Complex regulators of endolysosomal dynamics
Cell chemical biology·2025· 1 citedOpen Access
The hereditary spastic paraplegia type 21 (SPG21) protein is a RAB7A effector that promotes noncanonical mTORC1-catalyzed TFEB phosphorylation and cytoplasmic retention
Molecular Biology of the Cell·2025· 1 citedOpen Access
BLOC1S1 variants cause lysosomal and autophagic defects resulting in a hypomyelinating leukodystrophy with epileptic encephalopathy
2025Open Access
The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
Cell Reports·2024· 5 citedOpen Access
Biallelic <i>BORCS8</i> variants cause an infantile-onset neurodegenerative disorder with altered lysosome dynamics
Brain·2023· 22 citedOpen Access
Architecture of the ESCPE-1 membrane coat
Nature Structural & Molecular Biology·2023· 31 citedOpen Access
Inhibition of endolysosome fusion increases exosome secretion
The Journal of Cell Biology·2023· 38 citedOpen Access
The &lt;i&gt;Legionella pneumophila&lt;/i&gt; Effector DenR Hijacks the Host NRas Proto-Oncoprotein to Downregulate MAPK Signaling
SSRN Electronic Journal·2023Open Access
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 <sup>+</sup> lysosomes
Proceedings of the National Academy of Sciences·2022· 51 citedOpen Access
RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
Nature Communications·2022· 72 citedOpen Access
Measurement of Lysosome Positioning by Shell Analysis and Line Scan
Methods in molecular biology·2022· 11 citedOpen Access
The autophagy protein ATG9A enables lipid mobilization from lipid droplets
Nature Communications·2021· 111 citedOpen Access
Influenza Virus (A/HK/156/97) Hemagglutinin Expressed by an Alphavirus Replicon System Protects Chickens against Lethal Infection with Hong Kong-Origin H5N1 Viruses
UNC Libraries·2021Open Access
SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
Nature Communications·2021· 56 citedOpen Access
<i>Legionella pneumophila</i> targets autophagosomes and promotes host autophagy during late infection
2021Open Access
RUFY3 and RUFY4 are ARL8 effectors that couple lysosomes to dynein-dynactin
2021· 1 citedOpen Access
SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2-positive lysosomes
2020· 4 citedOpen Access
Membrane targeting activates Leucine-rich repeat kinase 2 with differential effects on downstream Rab activation
2020· 3 cited
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Frequent Co-authors

Juan S. Bonifacino(16), Anamaris M. Colberg‐Poley(11), Luis Bonet‐Ponce(6), Jillian H. Kluss(6), Mark Cookson(6), Michal Jarník(6), Alexandra Beilina(5), Yan Li(5), Amra Sarić(5), Raffaella De Pace(5), Julie G. Donaldson(4), Carlos M. Guardia(4), Petros Bozidis(4), David C. Gershlick(4), Patrick A. Lewis(4), Sara Sáez-Atiénzar(3), Natalie Landeck(3), Ravindran Kumaran(3), Christopher K. E. Bleck(3), Daniel S. Wong(3)