Miika Martikainen

Uppsala University — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index909citations19works8.02yr avg
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Research Topics

Virus-based gene therapy research(10), Mosquito-borne diseases and control(8), interferon and immune responses(6), Herpesvirus Infections and Treatments(5), RNA Interference and Gene Delivery(5)

Publications19 total

VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier
Nature Communications·2024· 8 citedOpen Access
VLDLR mediates alphavirus neuroinvasion through the blood-cerebrospinal fluid barrier
2023· 1 citedOpen Access
Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
Cancer Cell·2023· 117 citedOpen Access
IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma
Molecular Therapy — Oncolytics·2021· 21 citedOpen Access
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
Cell Death and Disease·2020· 178 citedOpen Access
Virus-Based Immunotherapy of Glioblastoma
Cancers·2019· 142 citedOpen Access
Abstract B175: Semliki Forest virus-mediated oncolytic immunotherapy in mouse GL261 glioblastoma model
Cancer Immunology Research·2019
Insertion of the Type-I IFN Decoy Receptor B18R in a miRNA-Tagged Semliki Forest Virus Improves Oncolytic Capacity but Results in Neurotoxicity
Molecular Therapy — Oncolytics·2017· 8 citedOpen Access
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins
Viruses·2017· 58 citedOpen Access
Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas
Translational Oncology·2017· 9 citedOpen Access
Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice
British Journal of Cancer·2017· 15 citedOpen Access
MicroRNA-Attenuated Clone of Virulent Semliki Forest Virus Overcomes Antiviral Type I Interferon in Resistant Mouse CT-2A Glioma
Journal of Virology·2015· 38 citedOpen Access
Identifying virus-host interactions critical for alphavirus-mediated oncolysis
2015· 1 citedOpen Access
Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model
Gene Therapy·2014· 35 cited
Attenuation of Semliki Forest Virus Neurovirulence by MicroRNA-Mediated Detargeting
Journal of Virology·2012· 60 citedOpen Access
Interferon-β Sensitivity of Tumor Cells Correlates With Poor Response to VA7 Virotherapy in Mouse Glioma Models
Molecular Therapy·2012· 20 citedOpen Access
SH3 Domain-Mediated Recruitment of Host Cell Amphiphysins by Alphavirus nsP3 Promotes Viral RNA Replication
PLoS Pathogens·2011· 134 citedOpen Access
Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice
PLoS ONE·2010· 64 citedOpen Access
Oncolytic SFV VA7 Vector Bearing Anti-Interferon IL-4 or IL-10 Insert Show Enhanced Replication in Mice
Scandinavian Journal of Immunology·2010

Frequent Co-authors

Magnus Essand(8), Ari Hinkkanen(8), Mohanraj Ramachandran(7), Di Yu(7), Markus Vähä‐Koskela(6), Janne Ruotsalainen(5), Roberta Lugano(4), Anna Dimberg(4), Minna Niittykoski(4), Kalle Saksela(3), Ilkka Pietilä(3), Jari Heikkilä(3), John C. Bell(3), Erkko Ylösmäki(2), Mikael von und zu Fraunberg(2), Arto Immonen(2), Susanna Koponen(2), Juha E. Jääskeläinen(2), Seppo Ylä‐Herttuala(2), Minttu-Maria Martikainen(2)