Janne Ruotsalainen

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index523citations17works0.02yr avg
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Research Topics

Virus-based gene therapy research(7), Immunotherapy and Immune Responses(5), Herpesvirus Infections and Treatments(4), RNA Interference and Gene Delivery(4), CAR-T cell therapy research(4)

Publications17 total

380 mRNA vaccination enhances TCRtg T cell therapy efficacy in solid tumors
Regular and Young Investigator Award Abstracts·2024Open Access
13.04 Improving the efficacy of TCRtg T cell therapy for solid tumors with mRNA-based vaccination
Oral Presentations·2024Open Access
CD4+ T cell-induced inflammatory killing controls immune evasive tumours
Research Square (Research Square)·2022· 1 citedOpen Access
The myeloid cell type I IFN system promotes antitumor immunity over pro‐tumoral inflammation in cancer T‐cell therapy
Clinical & Translational Immunology·2021· 9 citedOpen Access
Live or Let Die: T Cell Survival in Cancer Immunotherapy
Immunity·2019· 4 citedOpen Access
Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors
Experimental Dermatology·2018
Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
Immunity·2017· 267 citedOpen Access
Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice
British Journal of Cancer·2017· 15 citedOpen Access
Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles
BMC Veterinary Research·2015· 21 citedOpen Access
Interferon response as a challenge and possibility for developing alphavirus based oncolytic virotherapy
2014Open Access
Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model
Gene Therapy·2014· 35 cited
Synthesis of Cellulose Nanocrystals Carrying Tyrosine Sulfate Mimetic Ligands and Inhibition of Alphavirus Infection
Biomacromolecules·2014· 87 citedOpen Access
Inhibition of alphavirus infection with multivalent cellulose nanocrystals
Biomacromolecules·2014
Inhibition of alphavirus infection by multivalent cellulose nanocrystals: Tyrosine sulfate mimetics
2014
Interferon-β Sensitivity of Tumor Cells Correlates With Poor Response to VA7 Virotherapy in Mouse Glioma Models
Molecular Therapy·2012· 20 citedOpen Access
Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice
PLoS ONE·2010· 64 citedOpen Access
Oncolytic SFV VA7 Vector Bearing Anti-Interferon IL-4 or IL-10 Insert Show Enhanced Replication in Mice
Scandinavian Journal of Immunology·2010

Frequent Co-authors

Ari Hinkkanen(6), Miika Martikainen(5), Naveen Shridhar(4), Evelyn Gaffal(4), Thomas Tüting(4), Markus Vähä‐Koskela(4), Meri Rogava(3), Justin O. Zoppe(3), V. Ruottinen(3), Leena‐Sisko Johansson(3), Kristiina Järvinen(3), Jari Heikkilä(3), John C. Bell(3), Minna Niittykoski(3), Magnus Essand(3), Nicole Glodde(2), Tobias Bald(2), Tetje C. van der Sluis(2), Andreas J. Müller(2), Wolfgang Kastenmüller(2)