Christina A. Mitchell

Discovery Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

65h-index11.9kcitations311works5.52yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protein Kinase Regulation and GTPase Signaling(52), Cellular transport and secretion(41), PI3K/AKT/mTOR signaling in cancer(39), Dental materials and restorations(27), Bone Tissue Engineering Materials(21)

Publications311 total

Non-redundant roles of the phosphoinositide phosphatases PTEN and PIPP in PI3K/AKT signaling in breast cancer
Communications Biology·2025Open Access
The power of five – inositol polyphosphate 5‐phosphatase gene mutations at the intersection of development and disease
FEBS Letters·2025Open Access
Phosphoinositide phosphatases: Modifiers of phosphoinositide signaling in health and disease
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2025· 3 citedOpen Access
Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice
Nature Communications·2024· 19 citedOpen Access
A new role for phosphoinositides in regulating mitochondrial dynamics
Advances in Biological Regulation·2023· 11 citedOpen Access
Deterministic early endosomal maturations emerge from a stochastic trigger-and-convert mechanism
Nature Communications·2023· 19 citedOpen Access
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
Biochemical Society Transactions·2023· 10 citedOpen Access
Phosphoinositides in New Spaces
Cold Spring Harbor Perspectives in Biology·2023· 8 citedOpen Access
Supplementary Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
2023Open Access
Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
2023Open Access
Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
2023Open Access
Supplementary Data from Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
2023Open Access
PI(4,5)P <sub>2</sub> -dependent regulation of endothelial tip cell specification contributes to angiogenesis
Science Advances·2023· 13 citedOpen Access
Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models
International Journal of Molecular Sciences·2023· 4 citedOpen Access
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
2023· 1 citedOpen Access
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
2023Open Access
The FDA-Approved Drug Pyrvinium Selectively Targets ER+ Breast Cancer Cells with High INPP4B Expression
Cancers·2022· 7 citedOpen Access
Autophagic lysosome reformation in health and disease
Autophagy·2022· 82 citedOpen Access
Sequential conversion of PtdIns3P to PtdIns(3,5)P <sub>2</sub> via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy
Autophagy·2022· 7 citedOpen Access
Endosome maturation links <scp>PI3Kα</scp> signaling to lysosome repopulation during basal autophagy
The EMBO Journal·2022· 35 citedOpen Access
page 1 of 16Next →

Frequent Co-authors

Meagan J. McGrath(11), Lisa M. Ooms(10), Rajendra Gurung(10), Tony Tiganis(8), Adam D. Munday(6), Absorn Sriratana(5), Jennifer M. Dyson(5), Denny L. Cottle(5), Catriona McLean(4), Harshal Nandurkar(4), Belinda S. Cowling(4), S. Brown(4), Matthew J. Eramo(4), Benjamin J. Shields(3), Clare G. Fedele(3), Philip W. Majerus(3), Xiangming Zhang(3), Tony Rowe(3), Nicholas Dunne(3), Sarah E. Conduit(3)