Carsten Krebs

Pennsylvania State University — United States

Chemistry · Physical Sciences

76h-index17.8kcitations284works3.42yr avg
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Research Topics

Metal-Catalyzed Oxygenation Mechanisms(176), Metalloenzymes and iron-sulfur proteins(80), Porphyrin Metabolism and Disorders(53), Microbial metabolism and enzyme function(36), Photosynthetic Processes and Mechanisms(34)

Publications284 total

Experimental and Computational Analysis of the Inability of an Iron(II)- and 2-Oxoglutarate-Dependent Aliphatic Halogenase to Mediate Fluorination
2025Open Access
Experimental Evidence for Radical-Polar Crossover in Competition with, Rather Than Preceding, Alkene Formation by Microbial Ethylene-Forming Enzyme
Journal of the American Chemical Society·2025Open Access
Azetidine amino acid biosynthesis by non-haem iron-dependent enzymes
Nature Chemistry·2025· 2 citedOpen Access
A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen
Biochemistry·2025Open Access
Iron-sulfur clusters in SARS-CoV-2 exoribonuclease and methyltransferase complexes: relevance for viral genome proofreading and capping
Nature Communications·2025· 2 citedOpen Access
Biochemical Studies of a Cyanobacterial Halogenase Support the Involvement of a Dimetal Cofactor
Biochemistry·2025· 1 citedOpen Access
Heme Oxygenase–Like Metalloenzymes
Annual Review of Biochemistry·2025· 6 citedOpen Access
Structural Elucidation of the Reduced Mn(III)/Fe(III) Intermediate of the Radical-Initiating Metallocofactor in <i>Chlamydia trachomatis</i> Ribonucleotide Reductase
Biochemistry·2025· 2 citedOpen Access
Optimized Substrate Positioning Enables Switches in the C–H Cleavage Site and Reaction Outcome in the Hydroxylation–Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
Journal of the American Chemical Society·2024· 20 citedOpen Access
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO
Biochemistry·2024· 3 citedOpen Access
An Unusual Ferryl Intermediate and its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO
2024· 1 citedOpen Access
Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
2024· 1 citedOpen Access
Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
2024· 1 citedOpen Access
Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
2024· 1 citedOpen Access
Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
2024· 2 citedOpen Access
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production
Journal of the American Chemical Society·2024· 13 cited
An iron–sulfur cluster in the zinc-binding domain of the SARS-CoV-2 helicase modulates its RNA-binding and -unwinding activities
Proceedings of the National Academy of Sciences·2023· 39 citedOpen Access
Synergistic Binding of the Halide and Cationic Prime Substrate of <scp>l</scp> -Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States
Biochemistry·2023· 10 citedOpen Access
Synergistic Binding of the Halide and Cationic Prime Substrate of the l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States
2023· 2 citedOpen Access
Capturing a <i>bis</i>-Fe(IV) State in <i>Methylosinus trichosporium</i> OB3b MbnH
Biochemistry·2023· 5 citedOpen Access
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Frequent Co-authors

J. Martin Bollinger(34), Eric W. Barr(14), Boi Hanh Huynh(10), Squire J. Booker(8), John C. Price(6), Dale E. Edmondson(6), Wei‐chen Chang(6), Christopher T. Walsh(5), Lee M. Hoffart(5), Megan L. Matthews(5), Tyler L. Grove(4), Amie K. Boal(4), Jeffrey N. Agar(3), Jeverson Frazzon(3), Dennis R. Dean(3), Michael K. Johnson(3), Bo Zhang(3), Lana Saleh(3), Gang Xing(3), Elizabeth C. Theil(3)